4th International Eosinophil Symposium

要求为定于2005年5月25日至29日在瑞士伯尔尼大学医院举行的第四届两年一次的国际嗜酸性粒细胞专题讨论会和2007年第五届两年一次的专题讨论会提供财政支助。这些两年一次的会议是在国际嗜酸性粒细胞学会（IES）的主持下举行的。2005年会议将邀请41名全体发言人和另外120名与会者，请他们提交摘要，供青年科学家选择参加“尖端”口头介绍和海报展示会。会议开始于星期三的招待会/介绍会，5月25日，太阳结束，五月二十九日基础，转化和临床研究的前沿计划已由当地组织委员会与国际咨询委员会和IES执行委员会协商准备。研讨会为初级研究人员的口头和海报展示提供了绝佳的机会，并就这一生物医学重要，多样和跨学科领域的最新进展举行了全体会议。研讨会的特点是邀请领导人在嗜酸性粒细胞研究和相关领域从哮喘，过敏，肺，胃肠道和寄生虫病的角度，并包括一个新的保罗埃利希讲座，和主题演讲在嗜酸性粒细胞研究的未来方向。重点是嗜酸性粒细胞的细胞，分子和免疫生物学的两个基本方面，整合了嗜酸性粒细胞在正常生理和疾病发病机制中的作用的翻译和临床调查。今年增加了关于嗜酸性粒细胞胃肠道疾病、组织重塑和纤维化中的嗜酸性粒细胞、嗜酸性粒细胞增多综合征的新致病因素和抗嗜酸性粒细胞治疗策略的会议，包括讨论嗜酸性粒细胞生物学知识在药物治疗中的应用。 嗜酸性粒细胞相关疾病的发现。研讨会是一个高度互动的，研讨会一样，论坛的口头和海报介绍前沿摘要的年轻科学家，特别是研究生，博士后研究员，和初级教师。下午是故意不安排，以便有机会进行科学讨论，并在会议场地内外进行社交/娱乐活动。第四届研讨会的主题包括：（1）嗜酸性粒细胞发育、功能成熟的调节（激活和抑制）和死亡，（2）嗜酸性粒细胞疾病的动物模型，（3）嗜酸性粒细胞在胃肠道疾病中的作用，（4）嗜酸性粒细胞在先天免疫中的作用，（5）嗜酸性粒细胞对Th 2免疫应答的调节，（6）组织重塑和纤维化中的嗜酸性粒细胞，（7）嗜酸性粒细胞增多综合征的新致病因素，和（8）抗嗜酸性粒细胞治疗策略。 本次会议的中心目标是为初级和高级科学家在过敏，免疫学，血液学和癌症领域的科学交流和合作提供一个高度互动的论坛，涉及嗜酸性粒细胞在健康和疾病病理生理学的正常宿主生理学中的生物学和功能。

Financial support is requested for the 4th Biennial International Eosinophil Symposium, scheduled for May 25-29, 2005 at University Hospital, Bern, Switzerland, and the 5th Biennial Symposium in 2007. These biennial conferences are held under the auspices of the International Eosinophil Society (IES). The 2005 meeting will host 41 invited plenary speakers and an additional -120 participants who are solicited to submit abstracts for selection for "Cutting Edge" oral presentation and poster sessions by young scientists. The conference begins with a reception/orientation on Wed., May 25 and finishes on Sun., May 29. A cutting edge program of basic, translational, and clinical research has been prepared by the Local Organizing Committee in consultation with the International Advisory Committee, and the Executive Committee of the IES. The Symposium provides outstanding opportunities for oral and poster presentations by junior investigators, and plenary sessions on the most recent advances in this biomedically important, diverse and interdisciplinary field. The Symposium features invited talks by leaders in eosinophil research and allied fields from the perspectives of asthma, allergy, pulmonary, gastrointestinal and parasitic diseases, and includes a new Paul Erlich Lectureship, and Keynote Addresses on future directions in eosinophil research. The focus is on both basic aspects of eosinophil cellular, molecular and immunobiology, integrated with translational and clinical investigations of the roles of eosinophils in normal physiology and disease pathogenesis. Sessions on eosinophilic GI diseases, eosinophils in tissue remodeling and fibrosis, new pathogenic aspects of hypereosinophilic syndromes, and anti-eosinophil treatment strategies have been added this year, including discussions on applications of knowledge of eosinophil biology to drug discovery for eosinophil-associated diseases. The Symposium is a highly interactive, workshop-like, forum for both oral and poster presentations of cutting edge abstracts by younger scientists, particularly graduate students, postdoctoral fellows, and junior faculty. Afternoons are purposefully unscheduled to allow opportunities for scientific discussions, and social/recreational activities in and around the conference venue. The 4"' Symposium covers major themes on: (1) Regulation of Eosinophil Development, Functional Maturation (Activation and Inhibition), and Death, (2) Animal Models of Eosinophil Diseases, (3) Roles of Eosinophils in Gastrointestinal Diseases, (4) Eosinophils in Innate Immunity, (5) Eosinophil Regulation of Th2 Immune Responses, (6) Hosinophiis in Tissue Remodeling and Fibrosis, (7) New Pathogenic Aspects of Hypereosinophilic Syndromes, and (8) Anti-eosinophil Treatment Strategics. The central goal of this conference is to provide a highly interactive forum for scientific exchange and collaboration amongst junior and senior scientists in the fields of allergy, immunology, hematology, and cancer as relates to the biology and functions of the eosinophil in normal host physiology in health and pathophysiology in disease.