PROTEOMICS AND GENOMICS CORE FACILITY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Regarding AIDS ABSTRACT The Genomics and Proteomics Core at Meharry Medical College resulted from the reorganization into a single core of four RCMI-supported core facilities. These four cores were the Molecular Biology Core Facility (MBCF), the Molecular Neurobiology Core, the Computational Biology Core, and Information Technology. The new Genomics and Proteomics Core is a multifunctional entity with the objective of effectively providing the technical services and support required for research on genes and proteins. The Core is comprehensive since this Core provides access to the existing literature and databases to facilitate experimental design, the equipment and technical expertise to perform experiments on gene expression and protein interactions, and the computational resources for data analysis and data sharing. The specific functions of the Genomics and Proteomics Core at Meharry are: 1) to provide to the faculty, students and staff of Meharry Medical College the necessary expert personnel and equipment to provide the services of automated DNA sequencing, DNA microarray, and real-time PCR; 2) to stock an inventory of reagents for research and facilitate the purchase of molecular biological reagents for researchers; 3) to provide technical assistance with the use of shared equipment housed in the main and satellite laboratories; 4) to increase the access to electronic information sources including electronic journals and remote databases using the capacity and speed of Internet2; 5) to provide the technical expertise, hardware and software for the analysis of genetic, molecular and DNA microarray data; and 6) to provide a program of training in genomics and proteomics for faculty, staff and students. The ultimate goal of the Genomics and Proteomics Core is to provide services needed by the research community at Meharry to increase research productivity.