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中文摘要
翻译
初步规划阶段 汉普顿大学和匹兹堡大学癌症研究所之间的P20伙伴关系将是一个 与正在进行的项目评价和资源分配的优先次序进行动态协作。而 Co-Pi对伙伴关系的运作负有最终责任,他们将以建议为指导, 咨询委员会(IAC)的投入,由两个机构的内部顾问和外部顾问组成 在基因-环境相互作用方面具有国际公认的专业知识的专家。委员会成员 由机构领导提名和/或因具有特殊专长和参与方案而被选中。 委员会成员来自几个重要的学术学科, 强有力的多学科合作伙伴关系。通过在其学科中的领导角色,他们非常有资格 评估伙伴关系项目,确定克服后勤障碍的战略,并了解其他 教师或核心资源,可以刺激项目的成功增长。这一经验应有助于 为长期规划提供有益的投入,旨在维持机构内在分子方面的合作 流行病学和环境肿瘤学。来自汉普顿和匹兹堡的教师都很好 咨询委员会的代表,以便了解每个机构如何运作, 委员会审议。所有委员会成员都听取了关于合作的简报,并表示高度赞赏。 对伙伴关系的热情程度及其促进少数癌症研究人员成功的目标。 咨询委员会下设两个小组委员会,负责不同的监督和规划工作 责任这些机构是研究审查小组委员会和职业发展和 指导委员会(CDMC)。 研究审查委员会(RRC)由匹兹堡的丹尼尔约翰逊博士担任联合主席 来自汉普顿的马克·埃文斯博士将评估P20试点项目的进展, 审查半年度报告,并通过评价共同调查员的年度项目介绍, 的试点项目。 RRC联合主席丹尼尔约翰逊博士是匹兹堡大学医学副教授, 国际期刊《白血病》的联合编辑,NIH RO 1赠款的持续支持的接受者, 美国国立卫生研究院“药物发现和分子药理学”研究部门的常务成员。他还曾担任 作为美国癌症协会研究部门的正式成员, 美国血液学会年会。约翰逊医生还训练过汉普顿 在他的实验室里进行夏季研究轮换的本科生。 RRC联合主席Mark Davis。博士,是汉普顿大学生物系主任。 他的研究兴趣是人口科学。 RRC的其他成员包括: 劳拉·尼德恩霍夫。医学博士,NIH资助的DNA修复专家,专注于DMA修复的交叉点 机制和老化。她还共同指导医学博士的医学知识课程的研究基础 学生在匹兹堡,并经常指导本科学员。
英文摘要
INITIAL PLANNING STAGE The P20 partnership between Hampton University and the University of Pittsburgh Cancer Institute will be a dynamic collaboration with ongoing evaluation of projects and prioritization of resource allocation. While the Co-Pi's have ultimate responsibility for the functioning of the partnership, they will be guided by advice and input from an Advisory Committee (IAC) comprised of internal advisors from both institutions and an outside expert with internationally recognized expertise in gene-environment interaction. Committee members were nominated by institutional leadership and/or selected for special expertise and programmatic involvement. Committee members have been drawn from several academic disciplines important in the development of a strong multidisciplinary partnership. Through leadership roles in their disciplines, they are well qualified to evaluate partnership projects, to identify strategies to surmount logistic obstacles, and to know of additional faculty or core resources that can spur the successful growth of projects. This experience should facilitate useful input into long term planning aimed at sustaining intra-institutional collaborations in molecular epidemiology and environmental oncology. Faculty members from Hampton and from Pittsburgh are well represented on the Advisory Committee, so that an understanding of how each institution works frames committee deliberations. All Committee members had been briefed on the collaboration and expressed a high level of enthusiasm for the partnership and its goal of promoting the success of minority cancer researchers. There are two subcommittees of the Advisory Committee that have distinct oversight and planning responsibilities. These are the Research Review Subcommittee (RRC) and the Career Development and Mentoring Committee (CDMC). Research Review Committee (RRC) ¿ This committee, Co-Chaired by Dr. Daniel Johnson from Pittsburgh and Dr. Mark Evans from Hampton, will evaluate assess the progress of the P20 pilot projects and through review of semiannual reports and through evaluation of an annual Project Presentation by the Coinvestigators of the pilots projects. Daniel Johnson, PhD, Co-Chair of the RRC is Associate Professor of Medicine at the University of Pittsburgh, a Co-Editor of the international journal, Leukemia, a recipient of ongoing support from NIH RO1 grants and a standing member of the "Drug Discovery and Molecular Pharmacology" NIH study section. He has also served as a regular member of the American Cancer Society study section and is a frequent leader of sections at the annual meeting of the American Society of Hematology. Dr. Johnson has also trained Hampton undergraduates engaged in summer research rotations in his laboratory. RRC Co-Chair Mark Davis. PhD, is Chair of the Biology Department of Hampton University. His research interest is in Population Science. Other members of the RRC include: Laura Niedernhofer. MD-PhD a NIH-funded expert in DNA repair with a focus on the intersection of DMA repair mechanisms and aging. She also Co-Directs the Research Basis of Medical Knowledge course for MD-PhD students at Pittsburgh and has frequently mentored undergraduate trainees.
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Administrative Core
1/2- Feasibility study to build a collaboration in genetics and genomic cancer research
Administrative Core
1/2- Feasibility study to build a collaboration in genetics and genomic cancer research
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
芹菜素通过AGE-RAGE通路抑制干眼的炎症与氧化应激
  • 批准号:
    82505677
  • 项目类别:
    青年科学基金项目(C类)
  • 资助金额:
    30.00万元
  • 批准年份:
    2025
  • 负责人:
    吕雨霏
  • 依托单位:
麝香通心滴丸通过干预AGE-RAGE轴调节O-GlcNAc修饰发挥防治DCM作用的药效物质及机制研究
  • 批准号:
    82574874
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2025
  • 负责人:
    刘天华
  • 依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位: