Cesium 137 Irradiator: Model 68

铯 137 辐照器：型号 68

• 批准号: 6877383
• 负责人: STANTON L. GERSON
• 金额: $ 21.88万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6877383
• 关键词: biomedical equipment purchase; cell biology; neoplasm /cancer; radiation; stem cell transplantation; stem cells; veterinary science

DESCRIPTION (provided by applicant): The investigators request for the purchase of a small animal radiator, Mark I Cesium Irradiator model 68, to support NIH funded research in stem cell biology, stem cell transplantation and cancer. This request is timely because the seven investigators who will use this radiator have recently moved into the Wolstein Research Building of Case School of Medicine, CWRU. This building is not linked by internal passageways to the major animal facility of the Case School of Medicine or two sites housing current radiation equipment. Since radiation of mice and rats is an essential element to the NIH funded research of the requesting investigators, this piece of equipment will greatly enhance the ability to conduct animal research in a timely fashion. The irradiator will be housed within the twenty-eight thousand-cage clean barrier facility located in the sub-basement of the Wolstein Research Building. The radiator will be managed, as part of the Case Comprehensive Cancer Center Radiation Resource. All investigators housed in the Wolstein Building will utilize this facility for animal research. By placing the irradiator within the facility, it will be possible to maintain animals for prolonged periods of time without exposing these animals to pathogens in the environment. Currently no comparable piece of equipment is located within the Case School of Medicine that is accessible to these investigators. For this reason this is a high priority and its request for an essential piece of equipment to support the research of NIH funded investigators.

描述（由申请人提供）：研究者要求购买小动物辐射器Mark I Cesium Irradiator model 68，以支持NIH资助的干细胞生物学、干细胞移植和癌症研究。 这一要求是及时的，因为将使用这种散热器的七名研究人员最近搬进了CWRU凯斯医学院的Wolstein研究大楼。 这座建筑没有内部通道连接到凯斯医学院的主要动物设施或两个存放当前辐射设备的地点。 由于小鼠和大鼠的辐射是NIH资助的请求研究人员的研究的一个基本要素，这件设备将大大提高及时进行动物研究的能力。 辐照器将安置在位于Wolstein研究大楼地下室的28，000笼清洁屏障设施内。 辐射器将作为病例综合癌症中心辐射资源的一部分进行管理。 所有居住在Wolstein大楼的研究者将利用该设施进行动物研究。 通过将辐照器放置在设施内，可以长时间维持动物，而不会将这些动物暴露于环境中的病原体。目前，在凯斯医学院内没有类似的设备可供这些调查人员使用。 出于这个原因，这是一个高度优先事项，并要求一个必要的设备，以支持国家卫生研究院资助的研究人员的研究。