CRAFT Behavior Therapy Phase 2 Study: Tx Entry Component

CRAFT 行为疗法第二阶段研究：Tx 进入组件

• 批准号: 7273743
• 负责人: KIMBERLY C KIRBY
• 金额: $ 55.24万
• 依托单位: TREATMENT RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7273743
• 关键词: Abstinence; Aftercare; Alcohol or Other Drugs use; Behavior; Behavior Therapy; Behavioral; Caring; Clinical Research; Communities; Controlled Clinical Trials; Domestic Violence; Drug abuse; Drug usage; Drug user; Early Intervention; Educational Intervention; Educational process of instructing; Family; Family member; Funding; Goals; Grant; Health Personnel; Illicit Drugs; Intervention; Laboratories; Learning; Length; Manuals; Moods; National Institute of Drug Abuse; Outcome; Patients; Pharmaceutical Preparations; Phase II Clinical Trials; Prevalence; Principal Investigator; Probability; Procedures; Psychological reinforcement; Public Health; Randomized; Research; Research Personnel; Sampling; Services; Social Reinforcement; Societies; Specific qualifier value; Staging; Techniques; Testing; Training; Treatment Efficacy; Work; alcohol abstinence; base; contingency management; cost; design; drug abstinence; drug abuser; improved; problem drinker; programs; reinforcer; social; therapy development; voucher

DESCRIPTION (provided by applicant): The consequences of drug abuse are not limited to drug users; they also extend to their families and concerned significant others (CSOs). Research shows that CSOs of drug users have increased prevalence of illness, domestic violence, and problems in mood and functioning. Behavior therapy interventions, such as contingency management (CM) and the community reinforcement approach (CRA) have been among the most effective treatments for drug abuse. Financially-based CM is not well accepted by treatment providers, but our research indicates that social reinforcers are widely accepted. Because CSOs are troubled by the negative effects of drug use on the drug user and themselves, they may be a social community that is particularly invested in learning and implementing social reinforcers through CRA. In this application, we propose Stage II Behavior Therapy Development research on an intervention for CSOs known as Community Reinforcement and Family Training (CRAFT). This intervention teaches CSOs how to implement CRA, increasing the likelihood that the drug user will enter treatment and reduce drug use and improving CSO mood and functioning. Previous research conducted by Meyers, Miller and the principal investigator has accomplished the goals of Stage I research, including operationally defining and standardizing principles and techniques of CRAFT in manuals. In addition, early Stage II research demonstrated the efficacy of the therapy in three controlled clinical trials (Kirby et al., 1999; Meyers et al., 2002; Miller et al., 1999). This Stage II project will replicate previous findings and identify and explore the active components of CRAFT. Specifically, we will use a randomized controlled 2x2 design that will allow us to determine if the Treatment Entry Training (TEnT) component is necessary and sufficient to produce the primary and most consistent outcome of CRAFT -- treatment entry of the drug user. The main contributions of exploring the components of CRAFT will be twofold. First, identifying effective components of treatment can help focus subsequent studies of mechanisms of action, improving our scientific understanding and possibly leading to improvements in the quality of the intervention and second, identifying ineffective components of CRAFT can help reduce its length and cost, making a behavioral intervention that is already acceptable even more community-friendly. Thus, the proposed research will have both scientific and practical benefits for drug users and their CSOs.

描述（由申请人提供）： 吸毒的后果不仅限于吸毒者；他们还延伸到他们的家人和相关的重要其他人（CSO）。研究表明，吸毒者的公民社会组织增加了疾病、家庭暴力以及情绪和功能问题的患病率。行为治疗干预措施，例如应急管理（CM）和社区强化方法（CRA），一直是治疗药物滥用的最有效方法之一。以经济为基础的 CM 并未被治疗提供者广泛接受，但我们的研究表明，社会强化手段已被广泛接受。由于公民社会组织对吸毒对吸毒者及其自身的负面影响感到困扰，因此他们可能是一个特别投资于通过 CRA 学习和实施社会强化措施的社会团体。 在此申请中，我们提出了第二阶段行为治疗开发研究，对公民社会组织进行干预，称为社区强化和家庭培训 (CRAFT)。这种干预措施教会公民社会组织如何实施 CRA，增加吸毒者接受治疗、减少药物使用的可能性，并改善公民社会组织的情绪和功能。 Meyers、Miller 和首席研究员之前进行的研究已经实现了第一阶段研究的目标，包括在操作手册中定义和标准化 CRAFT 的原理和技术。此外，早期的 II 期研究在三项对照临床试验中证明了该疗法的功效（Kirby 等人，1999 年；Meyers 等人，2002 年；Miller 等人，1999 年）。该第二阶段项目将复制之前的发现，并识别和探索 CRAFT 的活性成分。具体来说，我们将使用随机控制的 2x2 设计，使我们能够确定治疗进入训练 (TEnT) 组件是否必要且足以产生 CRAFT 的主要且最一致的结果——吸毒者进入治疗。探索 CRAFT 组成部分的主要贡献将是双重的。首先，确定治疗的有效组成部分可以帮助集中后续的作用机制研究，提高我们的科学理解，并可能提高干预的质量；其次，确定 CRAFT 的无效组成部分可以帮助减少其时间和成本，使已经可以接受的行为干预更加适合社区。因此，拟议的研究将为吸毒者及其公民社会组织带来科学和实际的好处。