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Proteomics & Genomics Hands-On Workshop: From Sample Preparation to Data Analysis

蛋白质组学

基本信息

批准号：
7284295
负责人：
Nichole A Reisdorph
金额：
$ 14.21万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-05 至 2010-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7284295
关键词：
Access to Information Address Administrator Advertising American Animal Model Appendix Applications Grants Archives Area Arts Base Sequence Biochemistry Bioethics Bioinformatics Biological Biological Assay Biological Sciences Biology Biomedical Research Biometry Biotin Blood Book Reviews Calibration Charge Cheese Class Clinical Clinical Nutrition Cloning Cluster Analysis Coenzyme A Collaborations Collection Colorado Communication Complementary DNA Complex Computer software Congresses Copyright Core Facility Daily Data Data Analyses Data Set Data Sources Data Storage and Retrieval Databases Depth Development Digestion Drug Monitoring Education Educational Curriculum Educational Materials Educational process of instructing Educational workshop Electrospray Ionization Elements Ensure Epigenetic Process Evaluation Event Evolution Experimental Designs Exposure to Extensible Markup Language Faculty Feedback Flowcharts Fractionation Functional RNA Funding Future Gel Gene Expression Genes Genetic Transcription Genome Genomics Goals Graduate Education Grant Guidelines Hand Hand functions Health Sciences Healthcare Heart Hematological Disease High Pressure Liquid Chromatography Hour Human Human Resources Hybrids Imagery In Vitro Individual Industry Institutes Instruction International Internet Investigation Ions Joints Journals Knowledge Label Laboratories Language Lead Learning Letters Life Link Literature Lung Mails Manuals Manufacturer Name Maps Marketing Mass Spectrum Analysis Measurement Measures Mediation Metadata Methods MicroRNAs Microarray Analysis Modeling Molecular Biology Molecular Biology Techniques Monitor Nature Newsletter Northern Blotting Nucleic Acids Nucleotides Numbers Nutritional Study Online Systems Ontology Orthologous Gene Outcome Output Pamphlets Participant Pattern Peptides Performance Phosphopeptides Phosphoproteins Polymerase Chain Reaction Postdoctoral Fellow Preparation Principal Investigator Procedures Process Program Evaluation Property Proteins Proteome Proteomics Protocols documentation Provider Publications Published Comment Purpose Questionnaires RNA RNA Sequence Analysis Randomized Reaction Recruitment Activity Research Research Design Research Personnel Resolution Resources Reverse Transcriptase Polymerase Chain Reaction Review Committee Review Literature Role Rotation Running Sales Sample Size Sampling San Francisco Schedule Scholarship Science Scientist Score Sequence Analysis Services Site Sleep Disorders Small Interfering RNA Societies Solutions Source Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spottings Staining method Stains Standardization Structure Students Surveys System Systems Biology Teaching Method Techniques Technology Telephone Testing Therapeutic Time Toxicology Trainers Training Training Training Activity Training Programs Travel Two-Dimensional Gel Electrophoresis Unified Medical Language System United States National Institutes of Health Universities Update Validation Vendor Videotape Vision Visit Voting Week Wine Work Writing abstracting analytical method base comparative concept cost day design detector experience follow-up high school indexing instructor instrument instrumentation interest investigator training journal article lecturer lectures liquid chromatography mass spectrometry mass spectrometer member nano novel novel strategies nucleic acid purification outreach program performing art posters preference programs protein structure protein structure prediction research study response sample collection skills social group statistics success symposium theories three dimensional structure tool wiki

项目摘要

DESCRIPTION (provided by applicant): In recent years, genomics and proteomics have emerged as key technologies in biomedical research, resulting in a surge of interest in training by investigators keen to utilize these technologies in their research. Use of these advanced technologies requires trained personnel in order to produce valuable results, quality publications, and superior grant applications. To be of maximum benefit, education should ideally occur before experiments are begun, in order to lessen the possibility that the wrong platform is chosen. For example, a first step toward integrating "omics" technologies is the development of a well-stated hypothesis which clearly defines the research question under investigation. In order to test the hypothesis, the researcher must choose which platform to utilize and this requires an understanding of the technology available and the strengths and weaknesses of each approach. Alternatively, an investigator may determine that a combination of genomics and proteomics approaches is necessary. Careful experimental design is then critical to the success of the project as well as for interpreting the results. Given the large datasets generated by these technologies, knowledge of biostatistics, data analysis, and bioinformatics are vital and these are areas in which many investigators require additional training, specifically in the context of "omics" research. To address the issues outlined above, at least two types of training in "omics" technologies can be envisioned: 1) immediate, short-term training in the form of workshops, and 2) long-term, comprehensive instruction in the form of graduate education programs. The current proposal aims to fill the former need by providing hands-on training in genomics and proteomics in a coherent, experimentally-based framework. The Directors of the proposal have developed and taught courses covering Proteomics, Genomics, Bioinformatics, and Biostatistics and the curriculum for the proposed course will merge their expertise to provide a comprehensive training overview of these key technologies. Specifically, we propose to accomplish the following: build a curriculum enabling outcome-structured learning in proteomics and genomics technologies, provide novel training experiences using hands-on techniques and an established model by experienced investigators and educators, disseminate educational materials such that knowledge and information can be used to benefit a wide variety of audiences, and provide and/or act as portal for collaborative opportunities for both young and established investigators. (End of Abstract)

描述（由申请人提供）：