Ecstasy "Epidemic" and Youth: Trends, Comorbidity, Risk and Protective Factors

摇头丸“流行”与青少年：趋势、合并症、风险和保护因素

• 批准号: 7145914
• 负责人: PING WU
• 金额: $ 30.51万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-25 至 2009-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7145914
• 关键词: aging; behavior; child rearing; community; comorbidity; disease outbreaks; family; parents; sex

DESCRIPTION (provided by applicant): This revised R01 application is in response to the recent Program Announcement (PA-04-152): MDMA: Research Areas Needing More Emphasis. Its purpose is to study use of ecstasy (MDMA) in youth. With over 10 million people in the United States having used ecstasy at least once in their lives and majority of them being youth, there is an urgent need to understand the patterns and risk and protective factors associated with its use to be able to provide adequate prevention and intervention to this population. The proposed project is a secondary analysis of (1) data from a 7-year (1999-2005) series of annual surveys from the National Survey on Drug Use and Health (NSDUH, formerly called the National Household Survey on Drug Abuse (NHSDA)) and (2) the National Survey of Parents and Youth (NSPY), a longitudinal survey of youth and their parents on their substance use, and attitudes, beliefs and intentions towards substance use, and risk factors. Study aims: (1) To describe trends in ecstasy use from 1999 to 2005 in youth; to examine if the trends differ by gender, ethnicity and geographic area; to examine the effects of national policies on ecstasy use and on trends of ecstasy use in youth: (2) To examine ecstasy use in relation to use of other substances in youth. (3) To assess the relationship of ecstasy use with emotional and behavioral problems, as well as suicidal behaviors in youth, controlling for use of other drugs; to examine if the patterns of the relationships differ by gender; and (4) To assess risk and protective factors (at the individual level, family level, and community level) for ecstasy use in youth. To identify factors uniquely associated with ecstasy use and those shared with use of other substances. It is hoped that the findings of this project will help us to better understand patterns of ecstasy use, as well as risk and protective factors, and point the way to more specific research with clinical and policy relevance in this important field.

说明（由申请人提供）：此修订版 R01 申请是对最近的计划公告 (PA-04-152) 的回应：MDMA：需要更多重视的研究领域。其目的是研究青少年使用摇头丸 (MDMA) 的情况。在美国，有超过 1000 万人至少使用过一次摇头丸，其中大多数是年轻人，迫切需要了解与其使用相关的模式、风险和保护因素，以便能够为这一人群提供充分的预防和干预。拟议项目是对以下数据的二次分析：(1) 国家药物使用与健康调查 (NSDUH，以前称为国家药物滥用家庭调查 (NHSDA)) 的 7 年（1999-2005 年）系列年度调查数据和 (2) 全国父母和青少年调查 (NSPY)，一项针对青少年及其父母的药物使用情况以及对药物使用的态度、信念和意图以及风险的纵向调查 因素。研究目的： (1) 描述 1999 年至 2005 年青少年使用摇头丸的趋势；检查趋势是否因性别、种族和地理区域而异；审查国家政策对青少年使用摇头丸的影响以及对青少年使用摇头丸的趋势的影响： (2) 研究青少年使用摇头丸与使用其他药物的关系。 (3) 评估摇头丸的使用与情绪和行为问题以及青少年自杀行为的关系，并控制其他药物的使用；检查关系模式是否因性别而异； (4) 评估青少年使用摇头丸的风险和保护因素（个人层面、家庭层面和社区层面）。确定与摇头丸使用独特相关的因素以及与其他物质使用共有的因素。希望该项目的研究结果将帮助我们更好地了解摇头丸的使用模式以及风险和保护因素，并为这一重要领域中具有临床和政策相关性的更具体的研究指明道路。