Ecstasy "Epidemic" and Youth: Trends, Comorbidity, Risk and Protective Factors

本次修订的R01申请是对最近的计划公告(PA-04-152)的响应：MDMA： 需要更加重视的研究领域。其目的是研究摇头丸(MDMA)在青年中的使用情况。使用 在美国，超过1000万人一生中至少使用过一次摇头丸，其中大多数人 他们是年轻人，迫切需要了解他们的模式和风险以及保护因素 与其使用相关联，以便能够向这一人群提供充分的预防和干预。 拟议的项目是对(1)为期7年(1999-2005年)的一系列年度调查数据的二次分析 来自全国药物使用和健康调查(NSDUH，前身为全国家庭调查 关于药物滥用(NHSDA)和(2)全国父母和青少年调查(NSPY)，一项关于 关于青少年及其父母的药物使用情况，以及对药物使用的态度、信仰和意图， 和风险因素。 研究目的：(1)描述1999至2005年间青少年使用摇头丸的趋势；检验这些趋势是否有所不同 按性别、族裔和地理区域分列；审查国家政策对摇头丸使用和 青少年摇头丸使用趋势：(2)研究青少年摇头丸使用与其他物质使用的关系。 (3)评估摇头丸的使用与情绪和行为问题以及自杀的关系 青少年的行为，控制其他药物的使用；检查关系模式是否不同于 性别；以及(4)评估风险和保护因素(个人、家庭和社区) 水平)，在青年时期使用摇头丸。确定与摇头丸使用唯一相关的因素和共享的因素 与使用其他物质有关。 希望这个项目的发现将帮助我们更好地了解摇头丸的使用模式，以及 风险和保护因素，并为在临床和政策方面进行更具体的研究指明了方向 这个重要的领域。

This revised R01 application is in response to the recent Program Announcement (PA-04-152): MDMA: Research Areas Needing More Emphasis. Its purpose is to study use of ecstasy (MDMA) in youth. With over 10 million people in the United States having used ecstasy at least once in their lives and majority of them being youth, there is an urgent need to understand the patterns and risk and protective factors associated with its use to be able to provide adequate prevention and intervention to this population. The proposed project is a secondary analysis of (1) data from a 7-year (1999-2005) series of annual surveys from the National Survey on Drug Use and Health (NSDUH, formerly called the National Household Survey on Drug Abuse (NHSDA)) and (2) the National Survey of Parents and Youth (NSPY), a longitudinal survey of youth and their parents on their substance use, and attitudes, beliefs and intentions towards substance use, and risk factors. Study aims: (1) To describe trends in ecstasy use from 1999 to 2005 in youth; to examine if the trends differ by gender, ethnicity and geographic area; to examine the effects of national policies on ecstasy use and on trends of ecstasy use in youth: (2) To examine ecstasy use in relation to use of other substances in youth. (3) To assess the relationship of ecstasy use with emotional and behavioral problems, as well as suicidal behaviors in youth, controlling for use of other drugs; to examine if the patterns of the relationships differ by gender; and (4) To assess risk and protective factors (at the individual level, family level, and community level) for ecstasy use in youth. To identify factors uniquely associated with ecstasy use and those shared with use of other substances. It is hoped that the findings of this project will help us to better understand patterns of ecstasy use, as well as risk and protective factors, and point the way to more specific research with clinical and policy relevance in this important field.