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Graduate Training in Molecular Biophysics

Graduate Training in Molecular Biophysics
分子生物物理学研究生培训
批准号:
7256505
负责人:
GREGORY Duncan REINHART
金额:
$11.56万
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-07-01 至 2008-08-31

项目摘要

项目成果

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中文摘要
翻译
德克萨斯A&M大学和德克萨斯A&M大学健康科学中心的17个优秀研究小组在分子生物物理学(MB)方面创建了一个跨学科的研究生培训计划。培训教师的专业知识涵盖了广泛的研究技术和生物系统,从生物物理化学和生物分子光谱到结构和计算生物学。每个PI都致力于在分子水平上探索复杂的生物过程,实验重点从热力学到动力学,从单分子到多组分复合物,从可溶性到膜结合系统。这种多样性将为学员提供广泛的研究和课程内容以及深入的理解,确保MB的培训计划取得成功。MB教师在MB领域建立了富有成效的,外部资助的和装备精良的研究计划,并成功地指导和培训研究生。MB培训教师在五个不同的部门有主要的任命,但在研究,教学和期刊俱乐部合作互动的历史很强。与各个部门相关的研究生课程已经证明了他们有能力从美国各地招募优秀学生进行研究生学习,MB招聘将补充这些努力。学员将进入MB计划,并获得博士学位。通过两个部门之一。每年将有三名新学生获得MB奖学金,每个人都将获得博士学位最初两年的支持。study.在第一年,每个学生将做三个实验室轮换之前,从MB教师选择一个研究顾问,无论他/她的部门隶属关系。在最初的两年期间,甲基溴受训人员将接受关于基本生物物理和生物化学原则、负责任地进行研究以及解释和介绍研究结果的正式培训。将通过选修课程提供分子生物物理学各个方面的高级培训。学员将在整个研究生职业生涯中参加生物物理学杂志俱乐部,以提高他们的演讲技巧,并在第二年后保持对该计划的参与感。我们预计,MB培训计划的毕业生将能够在后基因组时代为生物医学科学做出重要贡献。
英文摘要
DESCRIPTION (provided by applicant): Seventeen outstanding research groups at Texas A&M University and the Texas A&M University Health Science Center have created an interdisciplinary graduate student training program in Molecular Biophysics (MB). The expertise of the training faculty spans a wide range of research techniques and biological systems, from biophysical chemistry and bio-molecular spectroscopy to structural and computational biology. Each PI is dedicated to exploring complex biological processes at the molecular level, and the experimental focus ranges from thermodynamics to kinetics, from single molecules to multi-component complexes, and from soluble to membrane-bound systems. This diversity will provide trainees with the breadth of research and course offerings and the depth of understanding that ensures a successful training program in MB. The MB faculty members have established productive, externally-funded, and well-equipped research programs in the MB area, and have been successful in mentoring and training graduate students. The MB training faculty members have primary appointments in five different departments, but share a strong history of collaborative interactions in research, in teaching, and in journal clubs. The graduate programs associated with individual departments have demonstrated their ability to recruit outstanding students from across the United States for graduate study, and MB recruiting will complement these efforts. Trainees will enter the MB program and receive their Ph.D. degrees through one of two departments. Three new students will receive an MB fellowship each year, and each will be supported for the initial two years of Ph.D. study. In the first year, each student will do three laboratory rotations prior to choosing a research advisor from the MB faculty, regardless of his/her departmental affiliation. During the initial two-year period, MB trainees will receive formal training in the fundamental biophysical and biochemical principles, the responsible conduct of research, and the interpretation and presentation of research results. Advanced training in various aspects of molecular biophysics will be provided by elective courses. Trainees will participate in the biophysics journal club throughout their graduate careers, both to improve their presentation skills and to maintain a sense of participation in the program following the second year. We anticipate that graduates of the MB training program will be well-positioned to make critical contributions to the biomedical sciences in the post-genomic era.
期刊论文(5)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1021/jp9105103
发表时间: 2010-01-21
期刊: The journal of physical chemistry. B
影响因子: --
作者: [McLean JR, McLean JA, Wu Z, Becker C, Pérez LM, Pace CN, Scholtz JM, Russell DH]
通讯作者: Russell DH
Kinetics analysis methods for approximate folding landscapes.
近似折叠景观的动力学分析方法。
DOI: 10.1093/bioinformatics/btm199
发表时间: 2007
期刊: Bioinformatics (Oxford, England)
影响因子: --
作者: [Tapia,Lydia, Tang,Xinyu, Thomas,Shawna, Amato,NancyM]
通讯作者: Amato,NancyM
Probing the determinants of diacylglycerol binding affinity in the C1B domain of protein kinase Cα.
探讨蛋白激酶 Cα C1B 结构域中二酰甘油结合亲和力的决定因素。
DOI: 10.1016/j.jmb.2011.03.020
发表时间: 2011
期刊: Journal of molecular biology
影响因子: 5.6
作者: [Stewart,MikaelaD, Morgan,Brittany, Massi,Francesca, Igumenova,TatyanaI]
通讯作者: Igumenova,TatyanaI
2012/2013 Enzymes, Coenzymes, and Metabolic Pathways Gordon Research Conference
  • 批准号:
    8510670
  • 项目类别:
  • 资助金额:
    $0.5万
  • 财政年份:
    2012
  • 负责人:
    GREGORY Duncan REINHART
  • 依托单位:
2012/2013 Enzymes, Coenzymes, and Metabolic Pathways Gordon Research Conference
  • 批准号:
    8389080
  • 项目类别:
  • 资助金额:
    $0.5万
  • 财政年份:
    2012
  • 负责人:
    GREGORY Duncan REINHART
  • 依托单位:
Graduate Training in Molecular Biophysics
MECHANISMS ON ALLOSTERIC INFLUENCES ON ENZYMES ACTIVITY
  • 批准号:
    6385525
  • 项目类别:
  • 资助金额:
    $30.12万
  • 财政年份:
    1983
  • 负责人:
    GREGORY Duncan REINHART
  • 依托单位:
国内基金
海外基金
Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
  • 批准号:
    81300605
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2013
  • 负责人:
    唐琳
  • 依托单位:
Molecular Plant
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
Molecular Plant