Biodefense and Emerging Infectious Diseases (BEID)

描述(由申请人提供)：建议的生物防御和新发传染病(BEID)培训计划的目的是培养能够支持与A-C类代理人或新发疾病代理人合作的生产性研究计划的独立调查人员。这从博士前水平开始，在感染性病原体的生物学以及这些病原体在动物模型中致病的机制方面进行广泛而严格的研究培训。拟议的培训计划的主要优势包括：1)佛罗里达大学(UF)中央行政部门为生物防御培训提供强大的机构智力和财政支持，以及三所组成学院(医学、牙科和兽医)提供的额外独立支持；2)在微生物发病机制和人类疾病的动物模型领域拥有富有成效的研究项目的已建立和认可的教职员工；以及3)培训目前在生物防御和新兴病原体领域进行研究的学生的记录。该计划由来自3所学院5个系的11名教员(细菌学家、病毒学家和寄生虫学家)组成。该计划的教职员工包括临床医生科学家，提供应用于人类传染病的动物模型的集成。博士前实习生将与密歇根大学生物医学跨学科项目(IDP)合作招募和初步培训。对于BEID学员，将针对与A、B和C类病原体和新出现的疾病病原体合作的科学、法律和监管方面进行专门培训。博士前培训包括大约5年，包括来自UF的第一年支持，平均2年来自培训补助金的支持，以及来自导师的研究资助或其他外部来源的其余支持。该计划的重点将是增强UF的现有优势，并为学员提供进行针对生物防御和新出现的疾病的研究所需的额外背景和技能集。

DESCRIPTION (provided by applicant): The aim of the proposed Biodefense and Emerging Infectious Diseases (BEID) training program is to produce independent investigators capable of sustaining productive research programs working with class A - C agents or agents of emerging diseases. This begins at the predoctoral level with broad, rigorous research training in the biology of infectious agents and the mechanisms by which these agents cause disease in animal models. Key strengths of the proposed training program include: 1) strong institutional intellectual and fiscal support for biodefense training from the central administration of the University of Florida (UF) plus additional, independent support from the three component colleges (Medicine, Dentistry and Veterinary Medicine); 2) established and recognized faculty with productive research programs in fundamental areas of microbial pathogenesis and animal models of human disease; and 3) a track record of training students who are currently conducting research in the areas of biodefense and emerging pathogens. The program comprises 11 faculty preceptors (bacteriologists, virologists, and parasitologists) from 5 departments within 3 colleges. The program faculty includes clinician scientists, providing integration of animal models as applied to human infectious disease. Predoctoral trainees will be recruited and initially trained in collaboration with the UF Interdisciplinary Program (IDP) in Biomedical Sciences. For BEID trainees, specialized training will be tailored to the scientific, legal, and regulatory aspects of working with Class A, B, and C agents and emerging disease pathogens. Predoctoral training encompasses approximately 5 years, including a first year of support from UF, an average of 2 years of support from the training grant and the remainder of support from the mentor's research grant or other external sources. The focus of the program will be to augment existing strengths at UF and provide trainees with additional background and skill sets necessary to conduct research directed towards biodefense and emerging diseases.