Pathology Core

病理学核心

• 批准号: 7160742
• 负责人: William M Baldwin
• 金额: $ 9.69万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7160742
• 关键词: biomedical facility; heart; immunopathology; inflammation; injury; ischemia; model; myocardial ischemia /hypoxia; pathology; proteins; reperfusion; role; transcription factor

The Immunopathology Core will provide the projects with uniform processing and staining of cells and tissues for microscopy. The core will offer expert immunohistochemistry on light and transmission electron microscopy (EM) for all tissue specimens from the projects. Most of the immunopathological methods employed are common to all of the projects so that a core laboratory will provide uniform methods and interpretation. The central processing of tissue will result in cost savings, quality control and comparability between the results of the projects. More importantly, it will provide an experienced pathologist in the field of inflammation and repair, who can compare and integrate the pathological findings in all of the models. The continual review of all of the histological findings by a single pathologist will ensure that both common and unique aspects of pathological results from different projects are appreciated immediately.

免疫病理学核心将为项目提供统一的细胞和组织处理和染色， 显微镜核心将提供光和透射电子显微镜（EM）的专家免疫组化 用于项目的所有组织标本。所采用的大多数免疫病理学方法是常见的 所有项目的核心实验室将提供统一的方法和解释。中央 组织的处理将导致成本节约，质量控制和结果之间的可比性， 项目更重要的是，它将提供一个有经验的病理学家在炎症和修复领域，谁 可以比较和整合所有模型中的病理结果。不断审查所有的 由一位病理学家进行的组织学发现将确保病理学的共同和独特方面 不同项目的成果立即得到赞赏。