PHENOTYPING CORE

表型核心

• 批准号: 7622775
• 负责人: KENNETH WARD
• 金额: $ 64.47万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7622775
• 关键词: Archives; Blood specimen; Clinical Data; Clinical Investigator; Collection; Computer Retrieval of Information on Scientific Projects Database; Condition; Data; Databases; Discipline of obstetrics; Funding; Future; Grant; High-Risk Pregnancy; Institution; Laboratories; Measurement; Midwife; Neonatal; Pathology; Patients; Perinatal; Phenotype; Physical Examination; Physicians; Protocols documentation; Research; Research Personnel; Research Subjects; Resources; Sampling; Source; Specimen; Standards of Weights and Measures; Techniques; Tissues; United States National Institutes of Health; clinical phenotype; follow-up; improved; neonate; repository

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Clinical Phenotype/Patient Sample Core will streamline access to clinical data and patient samples for the PRCEHD investigators and other clinical investigators at JABSOM. The clinical phenotyping component of the Core consists of a new perinatal/neonatal database, a new placental bank, and the option for a standardized neonatal examination and improved neonatal follow-up capability. The patient sample component of this Core will provide ascertainment and recruitment of potential research subjects, ongoing collection of relevant specimens, and efficient protocols to provide specimens to investigators and to store materials in a sample repository. Finally, the core laboratory will offer basic and advanced pathology techniques to current and future projects. The specific aims of this core are: 1) to build a new research database focused on perinatal and neonatal conditions, 2) to bank placental data and samples for all high-risk pregnancies for which standard pathological examinations were not requested by the attending physician or midwife, 3) to provide consistent and detailed physical examinations and anthropomorphic measurements on selected neonates, 4) to collect, access, archive, and distribute to the CCRE investigators high-quality tissue and blood specimens and relevant clinical data from obstetric and neonatal patients.

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