FEI TECNAI 12 SPIRIT BIO TWIN: CELL & MOLECULAR BIOLOGY

FEI TECNAI 12 SPIRIT BIO TWIN：细胞

• 批准号: 7335205
• 负责人: PAUL T. MATSUDAIRA
• 金额: $ 47.5万
• 依托单位: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-15 至 2007-04-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7335205
• 关键词: bioengineering /biomedical engineering; housing; income; molecular biology; teacher; twin /multiplet

This subproject is one of many research subprojects utilizing the resources provided by a Shared Instrumentation Grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the grant, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The Whitehead Institute requests $500,000 for the purchase of a FEI Technai 12 Spirit BioTwin TEM to be housed in the WM Keck Microscope Facility. The FEI TEM will up-grade the TEM services of the facility by replacing a twenty-year old Phillips 410 TEM. The 410 is nearing the end of its operational lifetime and maintenance is becoming difficult. More importantly, new generation FEI TEMs provide semi-automated operations for users and digital CCD-based imaging speeds and simplifies image capture, processing, and analysis for users and TEM technical staff. As an instrument in a core microscope facility, the TEM is widely used by Wl researchers. In addition, the same TEM is the only general use biological TEM on the MIT campus and serves labs in biology, bioengineering, engineering, chemistry, and other MIT departments. Furthermore, a significant number of researchers from the Boston-area also use the TEM. Thus, an up- graded TEM would benefit a significantly large research base. The proposal describes the research of six NIH-supported researchers and one new assistant professor at Tufts U. which does not have a biological TEM; To support the FEI Technai TEM, the Wl is committing an annual budget of $42,652 for an EM technician salary and maintenance contract. Furthermore, the Wl will pay $53,910 toward the purchase, shipping, and duty of the microscope.

该子项目是利用 NIH/NCRR 资助的共享仪器补助金提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是资助机构，不一定是研究者的机构。描述（由申请人提供）：Whitehead Institute 请求 500,000 美元购买 FEI Technai 12 Spirit BioTwin TEM，安装在 WM Keck 显微镜设施中。 FEI TEM 将通过更换使用了 20 年的 Phillips 410 TEM 来升级该设施的 TEM 服务。 410 的使用寿命已接近尾声，维护变得越来越困难。更重要的是，新一代 FEI TEM 为用户提供半自动化操作和基于数字 CCD 的成像速度，并为用户和 TEM 技术人员简化图像捕获、处理和分析。作为核心显微镜设施中的一种仪器，TEM 被 WI 研究人员广泛使用。此外，该 TEM 是 MIT 校园内唯一通用的生物 TEM，服务于生物学、生物工程、工程、化学和其他 MIT 院系的实验室。此外，来自波士顿地区的大量研究人员也使用 TEM。因此，升级后的 TEM 将有利于相当大的研究基地。该提案描述了 6 名 NIH 支持的研究人员和塔夫茨大学一名新助理教授的研究，塔夫茨大学没有生物 TEM；为了支持 FEI Technai TEM，Wl 承诺为 EM 技术人员工资和维护合同提供 42,652 美元的年度预算。此外，Wl 将支付 53,910 美元用于显微镜的购买、运输和关税。