Tissue Procurement Facility
组织采购设施
基本信息
- 批准号:7438468
- 负责人:
- 金额:$ 3.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-06-04 至 2010-05-31
- 项目状态:已结题
- 来源:
- 关键词:AccountabilityAutopsyBreastCancer CenterCancer PatientCellsClinicalCollectionConsentDataDatabasesEquipment and supply inventoriesFreezingFutureGene ExpressionLinkMalignant NeoplasmsMalignant neoplasm of prostateNormal tissue morphologyParaffin TissuePatientsPoliciesProcessRecommendationResearchResearch PersonnelResearch SupportResource SharingSerumServicesSpecimenStaining methodStainsStandardizationTissue ProcurementsTissuesTumor TissueUniversitiesbaseclinically relevantexperiencememberprogramsrepositorysurgery materialtumorvirtual
项目摘要
The overall objective of the Tissue Procurement Facility (TPF) is to procure and provide needed tissue
specimens to Stanford University Cancer Center investigators to support their cancer-related research.
TPF activities and services include collecting and banking freshly-frozen tumor and normal tissues from
excess surgical material and from autopsy, providing fresh tumor tissue for viable cell studies,
processing and banking serum specimens from cancer patients, maintaining a tissue database with links
to clinicopathological data, providing histological staining and pathological review, and coordinating
patient consent and assuring regulatory compliance. As a centralized Shared Resource, the TPF adds
value through experience, efficiency, standardization, accountability, protection of patient
confidentially, and timely completion of research. An advisory board provides recommendations on
facility policies and activities, and performs scientific and logistical review of service requests. In FY2005
the TPF, and satellite repositories, have provided tissue specimens to Cancer Center members
representing 8 out of 10 Programs. Highlights of the research supported by the Facility include the
discovery of clinically-relevant gene-expression subtypes of breast and prostate cancers. The TPF also
provides a portal to a "virtual bank" linking inventories of specialized "satellite" repositories, including
collections of hematological and neurosurgical specimens. Future plans include an expansion of
universal-consent based tissue procurement, increased efforts to bank both paraffin tissue blocks and
viable cells, and more detailed clinical annotation of tissue specimens.
组织采购机构(TPF)的总体目标是采购和提供所需组织
标本提供给斯坦福大学癌症中心的研究人员,以支持他们的癌症相关研究。
TPF的活动和服务包括收集和储存新鲜冷冻的肿瘤和正常组织
多余的手术材料和尸检,提供新鲜的肿瘤组织用于活细胞研究,
处理和储存癌症患者的血清标本,维护组织数据库,
临床病理学数据,提供组织学染色和病理学审查,并协调
患者同意并确保法规合规性。作为一个集中的共享资源,TPF增加了
通过经验、效率、标准化、问责制、患者保护实现价值
及时、准确地完成研究。一个咨询委员会就下列问题提出建议:
设施政策和活动,并对服务请求进行科学和后勤审查。在2005财政年度
TPF和卫星储存库向癌症中心成员提供了组织标本
代表了10个项目中的8个。基金资助的主要研究项目包括
发现乳腺癌和前列腺癌的临床相关基因表达亚型。TPF还
提供了一个“虚拟银行”的门户,链接专门的“卫星”储存库的库存,包括
收集血液学和神经外科标本。未来的计划包括扩大
基于普遍同意的组织采购,加大努力储存石蜡组织块,
活细胞和更详细的组织标本临床注释。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
JONATHAN R POLLACK其他文献
JONATHAN R POLLACK的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('JONATHAN R POLLACK', 18)}}的其他基金
Mechanisms and targeting of SWI/SNF alterations in pancreatic cancer
胰腺癌中 SWI/SNF 改变的机制和靶向
- 批准号:
8719605 - 财政年份:2014
- 资助金额:
$ 3.55万 - 项目类别:
Molecular Characterization of Sporadic Colorectal Cancer in the Young from India
印度年轻人散发性结直肠癌的分子特征
- 批准号:
7587366 - 财政年份:2008
- 资助金额:
$ 3.55万 - 项目类别:
Molecular Characterization of Sporadic Colorectal Cancer in the Young from India
印度年轻人散发性结直肠癌的分子特征
- 批准号:
7791370 - 财政年份:2008
- 资助金额:
$ 3.55万 - 项目类别:
Molecular Characterization of Sporadic Colorectal Cancer in the Young from India
印度年轻人散发性结直肠癌的分子特征
- 批准号:
7430672 - 财政年份:2008
- 资助金额:
$ 3.55万 - 项目类别:
Pathogenetics of a Clinically-favorable Prostate Cancer Subtype
临床上有利的前列腺癌亚型的发病机制
- 批准号:
7740168 - 财政年份:2007
- 资助金额:
$ 3.55万 - 项目类别:
Pathogenetics of a Clinically-favorable Prostate Cancer Subtype
临床上有利的前列腺癌亚型的发病机制
- 批准号:
7371760 - 财政年份:2007
- 资助金额:
$ 3.55万 - 项目类别:
Pathogenetics of a Clinically-favorable Prostate Cancer Subtype
临床上有利的前列腺癌亚型的发病机制
- 批准号:
7535266 - 财政年份:2007
- 资助金额:
$ 3.55万 - 项目类别:
相似海外基金
Elucidation of the role of perivascular macrophages in stroke using animal models for disease and autopsy brains
使用疾病动物模型和尸检脑阐明血管周围巨噬细胞在中风中的作用
- 批准号:
23K09773 - 财政年份:2023
- 资助金额:
$ 3.55万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Pathways to enrolling diverse Latinos in autopsy studies: Insights from a largelongitudinal study
让不同拉丁裔参加尸检研究的途径:大型纵向研究的见解
- 批准号:
10592154 - 财政年份:2023
- 资助金额:
$ 3.55万 - 项目类别:
Construction of the history of forensic medicine through medical and legal historiographical examination of autopsy reports from the founding period of medico-legal autopsy.
通过对法医学尸检创立时期尸检报告的医学和法律史学检查来构建法医学史。
- 批准号:
23K12072 - 财政年份:2023
- 资助金额:
$ 3.55万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
In situ and digital spatial profiling of the active HIV reservoir in autopsy-derived tissues
尸检组织中活性 HIV 储存库的原位和数字空间分析
- 批准号:
10459933 - 财政年份:2022
- 资助金额:
$ 3.55万 - 项目类别:
Developing an innovative statistical framework to integrate multiple verbal autopsy datasets to estimate cause-specific mortality
开发创新的统计框架来整合多个口头尸检数据集,以估计特定原因的死亡率
- 批准号:
10710402 - 财政年份:2022
- 资助金额:
$ 3.55万 - 项目类别:
Harmonizing Multiple Data Sources And Psychological Autopsy To Characterize Suicides Among Opioid-Related Deaths
协调多个数据源和心理尸检来描述阿片类药物相关死亡中的自杀特征
- 批准号:
10426651 - 财政年份:2022
- 资助金额:
$ 3.55万 - 项目类别:
Search for new biomarkers to assess cardiotoxicity: integrated analysis in autopsy heart
寻找新的生物标志物来评估心脏毒性:尸检心脏的综合分析
- 批准号:
22K06956 - 财政年份:2022
- 资助金额:
$ 3.55万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Histological examination of cardiac amyloid deposition and analysis of risk factors for sudden death: a forensic autopsy series.
心脏淀粉样蛋白沉积的组织学检查和猝死危险因素分析:法医尸检系列。
- 批准号:
20K18979 - 财政年份:2022
- 资助金额:
$ 3.55万 - 项目类别:
Grant-in-Aid for Early-Career Scientists