COMPARATIVE STUDIES OF PRIMATE BRAIN ORGANIZATION USING MRI

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。我们对人类大脑或黑猩猩大脑的连通性和区域组织知之甚少，黑猩猩是我们的近亲。这是因为神经科学家开发的研究大脑组织的大多数技术都需要侵入性和/或终端程序，这不适合在人类或黑猩猩身上使用。最近发展起来的磁共振成像(MRI)技术提供了在活体或自然死亡的生物体的固定组织中非侵入性地检查大脑区域和脑组织其他方面之间的联系的前景。我们正在改进这些技术，并应用它们来理解人类大脑与其他动物大脑的相似和不同之处。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have very little direct knowledge about the connectivity and regional organization of the human brain or that of chimpanzees, our closest relatives. This is because most of the techniques developed by neuroscientists for studying brain organization require invasive and/or terminal procedures, which are unsuitable for use in humans or in chimpanzees. Recently developed techniques using magnetic resonance imaging (MRI) offer the prospect of examining the connections between brain regions and other aspects of brain organization non-invasively in living organisms or in fixed tissue from organisms that have died of natural causes. We are refining these techniques and are applying them to understand how the human brain resembles and differs from that of other animals.