COMPARATIVE STUDIES OF PRIMATE BRAIN ORGANIZATION USING MRI

使用 MRI 对灵长类动物大脑组织进行比较研究

• 批准号: 7715759
• 负责人: JAMES K RILLING
• 金额: $ 2.85万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715759
• 关键词: Animals; Brain; Brain region; Comparative Study; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Human; Institution; Invasive; Knowledge; Life; Magnetic Resonance Imaging; Organism; Pan Genus; Pan troglodytes; Primates; Procedures; Relative (related person); Research; Research Personnel; Resources; Source; Techniques; United States National Institutes of Health; tissue fixing

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have very little direct knowledge about the connectivity and regional organization of the human brain or that of chimpanzees, our closest relatives. This is because most of the techniques developed by neuroscientists for studying brain organization require invasive and/or terminal procedures, which are unsuitable for use in humans or in chimpanzees. Recently developed techniques using magnetic resonance imaging (MRI) offer the prospect of examining the connections between brain regions and other aspects of brain organization non-invasively in living organisms or in fixed tissue from organisms that have died of natural causes. We are refining these techniques and are applying them to understand how the human brain resembles and differs from that of other animals.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们对人类大脑的连接和区域组织以及我们的近亲黑猩猩的大脑的连接和区域组织几乎没有直接的了解。 这是因为神经科学家开发的用于研究大脑组织的大多数技术都需要侵入性和/或终端程序，这不适合用于人类或黑猩猩。 最近开发的使用磁共振成像（MRI）的技术提供了非侵入性地在活生物体中或在来自自然原因死亡的生物体的固定组织中检查脑区域与脑组织的其他方面之间的连接的前景。 我们正在完善这些技术，并将其应用于了解人类大脑与其他动物的相似之处和不同之处。