OPERATOR TRAINING IN BIOLOGICAL MASS SPECTROMETRY

生物质谱操作员培训

• 批准号: 7369235
• 负责人: Catherine E. Costello
• 金额: $ 0.48万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7369235
• 关键词: OPERATOR; TRAINING; BIOLOGICAL; MASS; SPECTROMETRY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. ABSTRACT: Training on laboratory instruments is provided for investigators at various stages of their professional careers, in addition to the resident postdoctoral fellows. R. Theberge is responsible for training on the Bruker Reflex IV MALDI reflectron TOF MS, M. J. C. Miller for the Bruker Esquire ion trap and U. Sommer, for the ESI Quattro II triple quadrupole LC/MS system. Under the direction of these senior personnel, new postdoctoral fellows, visiting scientists and graduate students have learned to operate the introductory level instruments and to process and interpret the resulting data. During this year two international guests came for yearlong stays to learn all aspects of mass spectral analysis of proteins and other biomacromolecules: Ms. Jawon Seo, a graduate student at Ewha Women's University in Seoul, Korea, and Francesca Lavatelli, MD, from the Univ. of Pavia, Italy, who, upon her return, will take on responsibility for transthyretin analysis in samples obtained from familial amyloid patients at the hospital and ressearch center where she is employed.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。摘要：除了常驻博士后研究员外，还为处于职业生涯各个阶段的研究人员提供实验室仪器方面的培训。R. Theberge负责培训Bruker Reflex IV MALDI反射TOF MS，M。J. C.米勒的布鲁克Esquire离子阱和U。Sommer，用于ESI Quattro II三重四极杆LC/MS系统。在这些高级人员的指导下，新的博士后研究员、访问科学家和研究生学会了操作入门级仪器，并学会了处理和解释所得数据。在这一年里，两位国际客人来到这里，为期一年，学习蛋白质和其他生物大分子质谱分析的各个方面：韩国首尔梨花女子大学研究生Jawon Seo女士和意大利帕维亚大学医学博士Francesca Lavatelli回国后，她将在她工作的医院和研究中心负责从家族性淀粉样蛋白患者中获得的样本的甲状腺素运载蛋白分析。