PERMANENT SMALL ANGLE X-RAY SCATTERING STATION ON BEAM LINE 4-2

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。SSRL结构分子生物学小角X射线散射装置BL4-2是专门用于结构生物学研究的永久性实验站。它接收来自新的20极摇摆器波束的中央风扇辐射，该波束是去年作为SPEAR3升级的一部分安装的。Wiggler已经在缩小的Wiggler场中运行，以管理光学组件上的热负载，该组件将在2006年夏季关闭期间进行升级。该设施自2004年成为专用车站以来一直全面运营，并且一直超额预定。这是我们运行新仪器的第二个年头，它结合了传统的针孔几何小角散射相机和超小角度散射设置。所有用户都大大受益于新的自动改变样品到探测器距离的能力，并且能够覆盖所需的角度范围。USAXS安装作为机舱内系统的一个组成部分于今年投入使用。我们的结果表明，在这一点上，集成的仪器已经达到了与旧的独立USAXS仪器相当的基本技术指标。在具体的子项目中描述了显著的硬件和软件改进。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The SSRL Structural Molecular Biology small-angle x-ray scattering facility BL4-2 is a permanent experimental station dedicated for structural biology studies. It receives the central fan of radiation from the new 20-pole wiggler beam, which was installed as a part of the SPEAR3 upgrade last year. The wiggler has been operated at a reduced wiggler field to manage thermal load on the optic components, which will be upgraded during the summer shutdown in 2006. This facility has operated fully since becoming a dedicated station in 2004 and has been oversubscribed at all times. This has been our second year of running the new instrument, which combines the conventional pin-hole geometry small angle scattering camera and the ultra small angle scattering setup. All users benefited significantly from the new automated sample-to-detector distance change capability and were able to cover desired angular ranges. The USAXS setup was commissioned as an integrated part of the in-hutch system this year. Our results show that the integrated instrument has at this point achieved the basic specifications comparable to those of the older stand-alone USAXS instrument. Notable hardware and software improvements are described within the specific subprojects.