Characterisation of a UV-B-specific signalling pathway

UV-B 特异性信号通路的表征

• 批准号: BB/D019281/1
• 负责人: Gareth Islwyn Jenkins
• 金额: $ 49.09万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FD019281%2F1
• 关键词: Characterisation; UV; specific; signalling; pathway

UV-B wavelengths (280-320 nm) are an integral component of the daylight spectrum. UV-B induces physiological responses in plants, including changes in morphology and development and the regulation of various genes involved in secondary metabolism, chloroplast function and protection of the plant from damage by UV-B. Remarkably very little is known about how UV-B is perceived by plants and how it initiates responses. However, the first component involved in these processes has recently been identified, a protein called UVR8. The aim of this project is to characterise the UVR8 pathway, its interaction with other photoregulatory pathways and components, to understand how UV-B regulates UVR8 and to determine how UVR8 regulates transcription of target genes. Establishing how UVR8 is regulated and how it functions to control gene expresion will help us to understand how UV-B regulates aspects of plant growth and development and how plants survive in sunlight.

UV-B波长(280-320 nm)是日光光谱的组成部分。UV-B诱导植物的生理反应，包括形态和发育的变化以及参与次生代谢、叶绿体功能和保护植物免受UV-B伤害的各种基因的调节。值得注意的是，关于UV-B如何被植物感知以及它是如何启动反应的，人们知之甚少。然而，最近发现了参与这些过程的第一种成分，一种名为UVR8的蛋白质。本项目的目的是研究UVR8途径及其与其他光调节途径和组分的相互作用，了解UV-B如何调控UVR8，并确定UVR8如何调控靶基因的转录。确定UVR8是如何调控的，以及它是如何控制基因表达的，这将有助于我们理解UV-B如何调控植物生长发育的各个方面，以及植物如何在阳光下生存。

项目成果

UVR8 in Arabidopsis thaliana regulates multiple aspects of cellular differentiation during leaf development in response to ultraviolet B radiation

• DOI: 10.1111/j.1469-8137.2009.02855.x
• 发表时间: 2009-01-01
• 期刊: NEW PHYTOLOGIST
• 影响因子: 9.4
• 作者: Wargent, Jason J.;Gegas, Vasilis C.;Paul, Nigel D.
• 通讯作者: Paul, Nigel D.