Characterisation of a UV-B-specific signalling pathway

UV-B 特异性信号通路的表征

• 批准号: BB/D019281/1
• 负责人: Gareth Islwyn Jenkins
• 金额: $ 49.09万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FD019281%2F1
• 关键词: Characterisation; UV; specific; signalling; pathway

UV-B wavelengths (280-320 nm) are an integral component of the daylight spectrum. UV-B induces physiological responses in plants, including changes in morphology and development and the regulation of various genes involved in secondary metabolism, chloroplast function and protection of the plant from damage by UV-B. Remarkably very little is known about how UV-B is perceived by plants and how it initiates responses. However, the first component involved in these processes has recently been identified, a protein called UVR8. The aim of this project is to characterise the UVR8 pathway, its interaction with other photoregulatory pathways and components, to understand how UV-B regulates UVR8 and to determine how UVR8 regulates transcription of target genes. Establishing how UVR8 is regulated and how it functions to control gene expresion will help us to understand how UV-B regulates aspects of plant growth and development and how plants survive in sunlight.

UV-B波长（280-320 nm）是日光光谱的组成部分。 UV-B诱导植物的生理反应，包括形态学和发育的变化以及涉及继发代谢的各种基因，叶绿体功能以及对植物对UV-B损害的保护。关于植物如何看待UV-B及其如何启动反应，知之甚少。但是，最近已经确定了这些过程中涉及的第一个组件，一种称为UVR8的蛋白质。该项目的目的是表征UVR8途径，即它与其他光听力调节途径和组件的相互作用，以了解UV-B如何调节UVR8并确定UVR8如何调节靶基因的转录。确定UVR8的调节方式以及它如何控制基因扩展的功能将有助于我们了解UV-B如何调节植物生长和发育的各个方面，以及植物如何在阳光下生存。

项目成果

UVR8 in Arabidopsis thaliana regulates multiple aspects of cellular differentiation during leaf development in response to ultraviolet B radiation

• DOI: 10.1111/j.1469-8137.2009.02855.x
• 发表时间: 2009-01-01
• 期刊: NEW PHYTOLOGIST
• 影响因子: 9.4
• 作者: Wargent, Jason J.;Gegas, Vasilis C.;Paul, Nigel D.
• 通讯作者: Paul, Nigel D.