MULTIDETECTOR CT DIAGNOSIS OF PULMONARY EMBOLISM

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这是一项前瞻性观察性试验，旨在评估联合使用多探测器计算机辅助断层扫描（CT）血管造影和CT静脉造影诊断静脉血栓栓塞的阴性预测值。CT血管造影阴性的患者将在检测后随访3个月，以确定其是否有后续静脉血栓栓塞的证据。复发性静脉血栓栓塞的诊断将作为诊断性试验的参考标准，并确定试验的阴性预测值。理想情况下，这将使我们能够使用CT血管造影结合CT静脉造影作为肺栓塞诊断问题的一步解决方案。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a prospective observational trial to assess the negative predictive value of combined multidetector computer assisted tomography (CT) angiography and CT venography in the diagnosis of venous thromboembolism. Patient's with negative CT angiograms will be followed for 3 months after testing to determine whether or not they have evidence of subsequent venous thromboembolism. The diagnosis of recurrent venous thromboembolism will be the reference standard for diagnositc testing and to determine the negative predicted value of the test. Ideally, this will allow us to use CT angiography combined with CT venography as a one-step solution to the problem of pulmonary embolism diagnosis.