ND COBRE: CENTER FOR VISUAL NEUROSCIENCE: ADMINISTRATIVE CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。描述（由申请人提供）：本提案旨在在北达科他州立大学建立一个以视觉神经科学为主题的卓越生物医学研究中心（COBRE），以特别推进国家眼科研究所斜视、弱视和视觉处理项目的任务。该中心由三个主题相关的项目组成，每个项目由一名初级研究员指导，由现场和非现场的高级科学家导师协助，研究视觉感知、视觉认知和动作的神经机制和功能意义的各个方面。这四个项目，连同拟议的核心研究实验室、新教员招聘和行政核心设施，将有助于我们实现长远目标：发展一个多元化的、专注的、互动和协作的研究小组，致力于分析正常和功能障碍状态下的视觉表现，开发临床有用的评估视觉表现的诊断测试，了解在自然环境条件下控制眼球运动的神经机制，了解大脑如何处理视觉信息，神经活动如何与视觉感知相关，以及视觉处理如何与构成认知和行动基础的其他大脑系统相互作用。这个COBRE申请的具体目标是：1)为COBRE项目主管开发成功的、独立的、自我维持的研究项目，使未来能够成功获得R01资助；2)通过发展多用户核心实验室设施，加强NDSU生物行为学研究基础设施；3)通过增加两名在重点领域具有研究专长的教师，扩大NDSU在视觉神经科学方面的研究能力；4)在北达科他州立大学建立一个全国公认的视觉神经科学中心。这些具体目标的实现将在新大建立一个卓越的研究中心，吸引对视觉科学研究感兴趣的高素质教师、博士后和研究生。由此产生的中心将竞争机构培训补助金（T32）、研究项目补助金（R01）、核心补助金（P30）和基础设施发展补助金（R24），这些补助金将在最初的五年支持之后维持中心的运行。Blake， Legge和Tyler是外部咨询委员会的成员。Blakeslee和Nawrot组成了内部咨询委员会

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): This proposal is to establish a Center for Biomedical Research Excellence (COBRE) at North Dakota State University on the topic of VISUAL NEUROSCIENCE, which specifically advances the mission of the Strabismus, Amblyopia and Visual Processing program of the National Eye Institute. The proposed Center consists of three thematically interrelated projects, each directed by a junior investigator, assisted by onsite and off-site senior scientist mentors, which examine various aspects of the neural mechanisms and functional significance of visual perception, visual cognition and action. These four projects, together with proposed core research laboratories, new faculty recruitments, and administrative core facilities, will be instrumental in our attaining the long-range objective: To develop a diversely talented, yet focused, interactive and collaborative research group of critical mass devoted to analyzing visual performance in normal and dysfunctional states, to develop clinically useful diagnostic tests for assessing visual performance, to understand the neural mechanisms that control eye movements under natural environmental conditions, to understand how the brain processes visual information, how neural activity is related to visual perception, and how visual processing interacts with other brain systems which underlie cognition and action. The Specific Aims of this COBRE application are: 1) To develop successful, independent, self-sustaining research projects for the COBRE Project Directors to enable future success in obtaining R01 funding; 2) To enhance the biobehavioral research infrastructure at NDSU through the development of multi-user core laboratory facilities; 3) To expand NDSU's research capability in visual neuroscience by recruiting two additional faculty members with research expertise in key areas; 4) To establish a nationally recognized and acclaimed Center for Visual Neuroscience at North Dakota State University. The realization of these Specific Aims will establish a center of research excellence at NDSU that will attract quality faculty, postdoctoral fellows and graduate students interested in research in the visual sciences. The resulting Center will be competitive for Institutional Training Grants (T32), Research Project Grants (R01), Core Grants (P30) and Infrastructure Development Grants (R24) that will sustain the Center beyond the initial five years of support. Blake, Legge and Tyler are members of the External Advisory Committee. Blakeslee and Nawrot consitute the Internal Advisory Committ