Drug Abuse: Epidemiology, Treatment Process, & Outcomes

本申请是K05高级科学家奖的第二次重新提交，作为竞争延续 K02 DA00139。为了保持我的专业发展，K05的具体目标是：(1)发展 并应用先进的统计方法来提高对长期模式和后果的认识 药物使用、治疗过程和结果，以及药物使用模式与其他服务的相互作用 (2)培训和指导学生和初级调查人员；(3)为政策制定者、服务提供者、 和研究人员关于药物使用和治疗结果的长期模式和后果；以及(4) 巩固和广泛传播我在研究过程中积累的知识和经验 通过期刊文章、书籍和网站获得职业生涯。以过去完成的工作为基础，并 目前的研究生涯奖期间，我将继续通过开展3项研究来追求我的研究目标 研究项目：(1)加州36号提案对治疗系统的影响和结果的研究 (2)提供药物治疗以代替监禁)；(2)关于以下方面的机会和结果的研究 药物治疗和精神健康服务；以及(3)一个促进纵向药物滥用的中心项目 研究，其中我以前研究的档案数据也将在发现问题时进行分析。一个 特别强调与改进的开发相关的研究结果的影响 治疗战略和就社会政策变化提供咨询。我将继续提供培训和 为学生和初级调查人员提供指导，以帮助他们在职业生涯中取得进步。我的职业成长 将涉及继续开发和应用创新的统计方法，以支持我的 实质性的工作。我还将通过增加我的 与药物滥用研究相关的其他学科的知识，并通过合作工作。我的 与加州大学洛杉矶分校精神病学和生物行为系神经精神病学研究所(NPI)的联系 理科为我的职业发展提供了最佳的环境。在此背景下，我将进行研究 并将接受药物滥用治疗的临床方面的额外培训和实施 治疗服务。此外，我在药物滥用问题上的心理社会研究知识和技能将 通过补充NPI的生物行为，为加州大学洛杉矶分校药物滥用研究的一般计划做出贡献 透视。

This application is a second resubmission for a K05 Senior Scientist Award as a competing continuation of K02 DA00139. To sustain my professional development, the specific aims of this K05 are to: (1) develop and apply advanced statistical methods to improve the knowledge of long-term patterns and consequences of drug use, treatment process and outcomes, and the interplay of drug use patterns with other service systems; (2) train and mentor students and junior investigators; (3) advise policymakers, service providers, and researchers on long-term patterns and consequences of drug use and treatment outcomes; and (4) consolidate and widely disseminate the knowledge and experiences accumulated throughout my research career via journal articles, books, and a web site. Building upon work accomplished during the past and current Research Career Award periods, I will continue pursuing my research goals by conducting 3 research projects: (1) a study of treatment system impacts and outcomes of California's Proposition 36 (providing drug treatment in lieu of incarceration); (2) a study on the access and outcomes associated with drug treatment and mental health services; and (3) a Center project to advance longitudinal drug abuse research, in which archival data from my previous studies will also be analyzed as issues are identified. A special emphasis is on the implications of research findings pertinent to the development of improved treatment strategies and on providing advice on social policy changes. I will continue to provide training and mentorship to students and junior investigators to assist their career advancement. My professional growth will involve continued development and application of innovative statistical methodologies in support of my substantive work. I will also expand my capacity to conduct interdisciplinary research by increasing my knowledge regarding other disciplines relevant to drug abuse research and through collaborative work. My affiliation with the Neuropsychiatric Institute (NPI) in the UCLA Department of Psychiatry and Biobehavioral Sciences provides the optimum setting for my career development. In this context, I will conduct research and will receive additional training in clinical aspects of drug abuse treatment and in the implementation of treatment services. Furthermore, my psychosocial research knowledge and skills in drug abuse issues will contribute to UCLA's general program in drug abuse research by complementing NPI's biobehavioral perspective.