Real-Time Assessment of Triggers and Coping Responses in China

中国触发因素和应对反应的实时评估

• 批准号: 8507196
• 负责人: YIH-ING HSER
• 金额: $ 14.31万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-15 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8507196
• 关键词: AIDS/HIV problem; Abstinence; Address; Attention; Behavior Therapy; Behavioral; China; Chinese People; Chronic Disease; Cognitive; Collaborations; Communication; Communities; Coping Skills; Counseling; Data; Data Collection; Data Quality; Disease Management; Dropout; Drug Addiction; Drug abuse; Drug usage; Effectiveness; Environment; Feedback; Foundations; Future; Goals; HIV; HIV risk; Health; Health Personnel; Health Technology; Hepatitis C Transmission; Hepatitis C virus; Indium; Injecting drug user; International; Intervention; Knowledge; Link; Literature; Long-Term Care; Maintenance; Medical; Methadone; Mission; Monitor; Opiate Addiction; Opiates; Outcome; Outcome Measure; Patients; Pharmacotherapy; Phase; Pilot Projects; Provider; Public Health; Recovery; Relapse; Research; Research Personnel; Risk; Risk Behaviors; Self Management; Services; Social Environment; Technology; Testing; Text; Therapeutic; Time; Treatment Effectiveness; Urine; Validity and Reliability; base; coping; disorder later incidence prevention; effective intervention; evidence base; improved; innovation; methadone maintenance; novel; open source; prevent; prototype; response; skills; skills training; theories; therapy development; tool; treatment program

DESCRIPTION (provided by applicant): Responding to high rates of HIV/AIDS among opiate users, China has recently implemented methadone maintenance treatment (MMT) programs in order to reduce HIV risks among injection drug users (IDUs). While China has made strides in the implementation of MMT, high rates of continued opiate use and dropout among MMT patients remain problematic. Improved self-monitoring and self-management are important elements in chronic disease management, but these concepts are relatively new to Chinese MMT providers and patients. According to cognitive behavioral theories, managing triggers/risks and building coping skills are critical in relapse prevention and sustained recovery. A better understanding of common triggers and effective coping strategies among MMT patients will provide a foundation for developing effective interventions. Communication technologies and the proliferation of cellphones in China provide great opportunities to engage and network with patients and to collect ecological momentary assessment (EMA) data on triggers and coping responses. The proposed project will test the feasibility and acceptability of EMA data collection of triggers and coping responses using cellphone and text messaging technology. An open-source mobile health platform, called "ANDWellness," has been developed by UCLA researchers for supporting self-monitoring and behavioral interventions. We propose to build upon this innovative platform to conduct real-time assessment of triggers and coping responses among MMT patients in China. The study aims are (1) To develop an interactive cellphone-supported mobile health prototype that establishes individualized profiles of risks or triggers and that supports knowledge and skill building, including coping strategies; and (2) To conduct a pilot study to assess the reliability and validity of the EMA data. A secondary objective is to obtain preliminary evidence on self-monitoring in relation to outcome data (e.g., MMT retention, abstinence). The project will be accomplished in two phases: Phase I will develop a smartphone-based prototype of the ANDWellness application. We will also assess the acceptability and feasibility of the prototype. Phase II will consist of a pilot test to examine th acceptability of and compliance with the ANDWellness prototype collecting EMA data on triggers and responses, the correspondence of EMA with the retrospective recall and urine testing, and the relation between EMA and some limited outcomes. These pilot efforts will prepare us for future intervention development based on cellphone technology. The long-term goal of this line of research is to develop promising strategies that optimize treatment effectiveness and support sustained recovery by taking advantage of the popularity of cellphone use, and adapting and applying evidence-based principles to address drug use and HIV/HCV risk behaviors. Thus, the study will contribute to the literature on triggers and coping strategies and will extend NIDA's mission of promulgating research-based interventions to improve treatment services and reduce HIV/HCV transmission globally.

描述（由申请人提供）：响应阿片用户中的艾滋病毒/艾滋病的高率，中国最近实施了美沙酮维护治疗（MMT）计划，以降低注射吸毒者（IDU）的艾滋病毒风险。尽管中国在实施MMT方面取得了长足的进步，但MMT患者的鸦片使用和辍学率很高，仍然有问题。改善的自我监控和自我管理是慢性疾病管理中的重要因素，但是这些概念对中国MMT提供者和患者来说是相对较新的。根据认知行为理论，管理触发因素/风险和建立应对技巧对于预防复发和持续恢复至关重要。对MMT患者的常见触发因素和有效应对策略的更好理解将为制定有效的干预措施提供基础。通信技术和中国手机的扩散为与患者互动和联系并收集有关触发器和应对反应的生态瞬时评估（EMA）的数据提供了绝佳的机会。拟议的项目将使用手机和文本消息技术来测试EMA数据收集以及应对响应的可行性和可接受性。 UCLA研究人员开发了一个名为“ Andwellness”的开源移动健康平台，用于支持自我监控和行为干预措施。我们建议以这个创新的平台为基础，以对中国MMT患者的触发器进行实时评估和应对反应。该研究的目的是（1）开发一个交互式手机支持的移动健康原型，该原型建立了风险或触发器的个性化概况， 支持知识和技能建设，包括应对策略； （2）进行试点研究以评估EMA数据的可靠性和有效性。第二个目标是获得有关结果数据的自我监控的初步证据（例如，保留MMT，禁欲）。该项目将分为两个阶段：第一阶段将开发基于智能手机的AndWellness应用程序的原型。我们还将评估原型的可接受性和可行性。第二阶段将包括一个试验测试，以检查对触发器和响应的EMA数据的可接受性和符合性的符合性，EMA与回顾性召回和尿液测试的对应关系以及EMA之间的关系和一些有限的结果之间的关系。这些试点努力将为我们做好基于手机技术的未来干预开发的准备。这一研究的长期目标是制定有希望的策略，通过利用手机使用的普及以及适应和应用基于证据的原则来解决药物使用和HIV/HCV风险行为，从而优化治疗效率和支持持续恢复。因此，该研究将有助于有关触发器和应对策略的文献 并将扩大NIDA颁布基于研究的干预措施以改善治疗服务并在全球范围内减少HIV/HCV传播的使命。