Novel Photon Counting Clinical CT Detectors

新型光子计数临床 CT 探测器

• 批准号: 7482068
• 负责人: WILLIAM C BARBER
• 金额: $ 14.2万
• 依托单位: DXRAY, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7482068
• 关键词: Address; Algorithms; Anodes; Area; Binding; Calcified; Calcium; Ceramics; Clinical; Code; Collaborations; Compatible; Computer software; Computers; Consumption; Contrast Media; Count; Coupled; Custom; DAQ; Data; Detection; Development; Diagnostic radiologic examination; Dimensions; Discrimination; Dose; Electronics; Encapsulated; Fibrosis; Floods; Floor; Gadolinium; Goals; Grant; Histocompatibility Testing; Image; Imaging Phantoms; Imaging Techniques; Imaging technology; Individual; Iodine; Lateral; Literature; Mammography; Manufacturer Name; Marketing; Measures; Mechanics; Methods; Mind; Modeling; Morphologic artifacts; Motor; Noise; Numbers; Object Attachment; Operating System; Output; Patients; Performance; Phase; Photons; Physiologic pulse; Polychlorinated Biphenyls; Power Sources; Printing; Property; Pulse taking; Radiation; Range; Rate; Reading; Records; Research; Resolution; Risk; Roentgen Rays; Running; Sampling; Scanning; Semiconductors; Side; Signal Transduction; Simulate; Slice; Small Business Funding Mechanisms; Small Business Innovation Research Grant; Solid; Source; Speed; Staging; Standards of Weights and Measures; Surface; System; Technology; Temperature; Testing; Thick; Tissues; Tube; United States; Universities; Weight; Width; X-Ray Computed Tomography; base; bone; cadmium telluride; cold temperature; commercialization; cost; data acquisition; density; design; detector; feeding; improved; irradiation; new technology; next generation; novel; physical property; programs; prototype; reconstruction; response; simulation; size; soft tissue; statistics; tumor; voltage

DESCRIPTION (provided by applicant): Photon counting detectors with energy binning can improve CT performance by counting and binning each x-ray detected. Photon counting x-ray detectors applied to mammography and radiography have shown a dose reduction of 40% to 400% while maintaining sufficient contrast for these applications. For use in CT these detectors are limited, due to an upper bound in terms of their maximum count rate, and advances in maximum count rate capabilities is needed. In order to overcome count rate limitations, new technological developments in reducing the size of application specific integrated circuits (ASICs) has been applied to reading out semiconductor detectors. These advancements, along with improvements to the cost and reliability of the compound semiconductor cadmium telluride (CdTe), allow us to develop a photon counting detector and read-out technology for CT. Therefore the overall goal of this Fast Track Phase I/Phase II proposal is to develop a photon counting CT detector with energy binning and read-out that is capable of producing energy resolved CT scan which can deliver less radiation dose and differentiate between tissue types.

描述（由申请人提供）：具有能量分箱功能的光子计数探测器可通过对探测到的每条X射线进行计数和分箱来提高CT性能。应用于乳房X射线照相术和X射线照相术的光子计数X射线探测器显示出40%至400%的剂量减少，同时保持这些应用的足够对比度。对于在CT中的使用，这些探测器由于其最大计数率方面的上限而受到限制，并且需要最大计数率能力的进步。为了克服计数率限制，减小专用集成电路（ASIC）尺寸的新技术发展已经应用于阅读半导体检测器。这些进步，沿着化合物半导体碲化镉（CdTe）的成本和可靠性的改善，使我们能够开发用于CT的光子计数探测器和读出技术。因此，本快速通道I期/II期提案的总体目标是开发一种具有能量分箱和读出功能的光子计数CT探测器，该探测器能够产生能量分辨CT扫描，能够提供更少的辐射剂量并区分组织类型。