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DESCRIPTION (provided by applicant): This research is aimed at exploring, developing, and evaluating a new type of computed radiography (CR) for digital mammography. This approach is designed to overcome the well-known limitations of current CR technology that are associated with supoptimal spatial resolution and dose efficiency. CR technology is the low cost approach to digital mammography but it has never been used clinically in the US due to the slow pace of development and the lack of a trully innovative approach. The proposed approach represents a radical departure from prior technology. It incorporates readily-available components, and integration can be inexpensive. The results of our extensive computational and experimental work, that suggest good image quality and dose efficiency, will be used to develop a prototype that incorporates the components for scanning CR plates. This would enable high optical signal capture efficiency, faster readout, good spatial resolution, compact size, and low cost. Evaluation of the electronic, optical and mechanical characteristics of the system will be performed that will prompt modifications for improved performance. Universally accepted methodology such as modulation transfer function and detective quantum efficiency will be applied for the evaluation of the imaging capabilities and overall performance of the new imaging system. Threshold contrast detail studies will be conducted to compare its performance with current technologies. It is anticipated that this new digital x-ray imaging approach will enable greater contrast and spatial resolution than existing state-of-the-art CR technology that has been attempted for digital mammography. CR technology is ideally suited and desperately needed for cost efficient digital mammography but the current technology has not yet met the high image quality standards that are required for this task. This research deals not only with the development of a protoype but also with the theoretical formulation to predict the performance of the proposed and aother types of CR devices under a variety of conditions. This would enable the development of state-of-the art CR devices that are equivalent or better to other x-ray imaging modalities with the added advantage of portatbility and ease of integration. The potential impact of this inherently low-cost high resolution CR plate reader in a cassette-like package can be very high as it can be easily adapted to the needs of current clinical practice.
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Modeling the performance characteristics of computed radiography (CR) systems.
对计算机放射成像 (CR) 系统的性能特征进行建模。
DOI: 10.1109/tmi.2009.2036995
发表时间: 2010
期刊: IEEE transactions on medical imaging
影响因子: 10.6
作者: [Vedantham,Srinivasan, Karellas,Andrew]
通讯作者: Karellas,Andrew
Upright, Low-dose, High-resolution, 3D Breast CT
  • 批准号:
    9810897
  • 项目类别:
  • 资助金额:
    $76.37万
  • 财政年份:
    2019
  • 负责人:
    Andrew Karellas
  • 依托单位:
High-resolution lower dose dedicated breast CT
  • 批准号:
    9925061
  • 项目类别:
  • 资助金额:
    $57.8万
  • 财政年份:
    2017
  • 负责人:
    Andrew Karellas
  • 依托单位:
New Technology for Computed Radiography
New Technology for Computed Radiography
  • 批准号:
    7124650
  • 项目类别:
  • 资助金额:
    $59.28万
  • 财政年份:
    2005
  • 负责人:
    Andrew Karellas
  • 依托单位:
国内基金
海外基金
Handbook of the Mathematics of the Arts and Sciences的中文翻译
  • 批准号:
    12226504
  • 项目类别:
    数学天元基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2022
  • 负责人:
    黄朝凌
  • 依托单位:
ARTS在邻苯二甲酸(2-乙基己基)酯诱导的小鼠睾丸间质细胞凋亡中的作用及机理研究
  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    35万元
  • 批准年份:
    2020
  • 负责人:
    陈加祥
  • 依托单位:
ARTS在邻苯二甲酸(2-乙基己基)酯诱导的小鼠睾丸间质细胞凋亡中的作用及机理研究
  • 批准号:
    82060278
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    35.0万元
  • 批准年份:
    2020
  • 负责人:
    陈加祥
  • 依托单位:
促进肿瘤凋亡的融合蛋白CPP-TRAIL-ARTS C27的制备及机制研究
  • 批准号:
    81372444
  • 项目类别:
    面上项目
  • 资助金额:
    70.0万元
  • 批准年份:
    2013
  • 负责人:
    易成
  • 依托单位: