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Multimodal Neuroimaging Training Program

多模态神经影像培训计划

基本信息

批准号：
7477688
负责人：
SEONG KIM
金额：
$ 7.69万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-30 至 2011-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7477688
关键词：
Action Potentials Address Advisory Committees Alzheimer&apos s Disease Anatomy Animals Attention Autistic Disorder Basal Ganglia Base of the Brain Basic Science Behavior Behavioral Sciences Biological Neural Networks Biology Brain Brain Injuries Brain imaging Brain region Cellular biology Cerebellum Clinical Cognition Cognitive Cognitive Science Collaborations Communication Communities Computer Simulation Computer information processing Computer software Computing Methodologies Coupled Data Data Analyses Dendrites Depth Detection Development Discipline Doctor of Philosophy Education Educational Curriculum Educational process of instructing Educational workshop Elements Engineering Ensure Environment Ethics Evaluation Event Exercise Experimental Designs Exposure to Faculty Feedback Fellowship Focus Groups Fourier Transform Frequencies Functional Magnetic Resonance Imaging Funding Gene Expression Regulation Goals Graduate Education Grant Hand Hippocampus (Brain)Home environment Hour Human Image Image Analysis Imagery Imaging Techniques Impaired cognition Individual Institutes Institution Interdisciplinary Study Internet Knowledge Laboratories Laboratory Research Language Learning Libraries Linguistics Literature Machine Learning Magnetic Resonance Imaging Magnetoencephalography Mathematics Measures Medical Imaging Membrane Potentials Memory Mental disorders Mentors Methodology Methods Modality Modeling Molecular Molecular Neurobiology Monitor Motor Cortex Multimodal Imaging National Center for Research Resources National Institute of Mental Health National Research Service Awards Nervous system structure Neuroanatomy Neurobiology Neurons Neurosciences Neurosciences Research Numbers Optics Paper Participant Perception Performance Pharmacology Physics Physiological Physiology Play Positioning Attribute Positron-Emission Tomography Principal Investigator Procedures Process Productivity Program Evaluation Protein Chemistry Psyche structure Psychology Range Reading Recommendation Reporting Research Research Methodology Research Personnel Research Project Grants Research Proposals Research Training Resolution Role Rotation Running Schools Scientist Second Messenger Systems Series Signal Transduction Slide Specimen Speed Structure Student Selections Students Suggestion Surveys Synaptic Transmission Synaptic plasticity System Techniques Technology Time Tissues Training Training Activity Training Programs United States National Institutes of Health United States National Library of Medicine Universities Virus Visit Visual system structure Voting Week Work Writing base bioimaging brain metabolism cognitive neuroscience computational neuroscience computerized data processing concept data acquisition data modeling day design electrical property executive function experience improved in vivo independent component analysis insight interest international center lectures ligand gated channel member neuroimaging novel optical imaging physical science pre-doctoral professor programs receptor function relating to nervous system research study response second messenger sensorimotor system simulation skills success symposium voltage

项目摘要

DESCRIPTION (provided by applicant): The goal of this research is to enable the development of novel interdisciplinary training programs that integrate two components 1) an NRSA predoctoral training program and 2) a Short-Term Research Education Program, which will include a non-NRSA predoctoral training program. There have been great advances in in vivo imaging techniques, which allow neuroscientists to visualize molecular, cellular, and system physiology and functions. To fully utilize neuroimaging techniques, it is important to understand underlying principles, data detection, and data modeling and visualization. Furthermore, each technique has its own strengths and limitations. In order to overcome the weakness of one neuroimaging modality, it is absolutely essential to utilize complementary imaging modalities. Often, researchers may not utilize advanced neuroimaging technologies due to the lack of proper training in these methodologies, therefore, it is crucial to train students the principles and limitations of multiple neuroimaging modalities. In order to achieve this goal, we propose to create the Multimodal Neuroimaging Training Program (T90/R90) for predoctoral and short-term summer students, which will be jointly run by the University of Pittsburgh and Carnegie Mellon University. This program will be administered by the Center for the Neural Basis of Cognition (CNBC), which seamlessly spans both institutes and is a coordinated interdisciplinary research and educational Center of international stature. Specific aims of the predoctoral training program are to 1) teach basic neuroscience for integrative neuroimaging research; 2) to teach underlying principles, modeling, and applications of structural magnetic resonance imaging (MRI), functional MRI, positron emission tomography, magnetoencephalography, and optical imaging from animals to humans; and 3) to integrate multiple methods and carry out multimodal neuroimaging projects. To achieve the specific aims, trainees will take core courses and laboratory rotations, seminars and participate in an annual retreat. In addition to the graduate T90/R90 training program, the short-term Multimodal Neuroimaging Summer School (R90) is proposed to teach the synergy of multi-modal neuroimaging for targeted students and investigators who have experience in one imaging modality and want to expand their training to other modalities. The summer program will consist of basic lectures, hand-on laboratory workshop, and performing projects, emphasizing the methodologies of multiple imaging modalities. Our proposed program will train researchers for adequate handling of the increasing complexity of combining multimodal neuroimaging data with the knowledge of various data acquisition and processing approaches, and appropriate interpretations. This will speed up the synergetic application of multiple imaging modalities to basic and clinical neuroscience research in animals and humans. All training faculty have an exceptional track record of effective interdisciplinary training and cooperative research. The materials developed in this Training Program will be distributed through the web.

描述（由申请人提供）：本研究的目标是开发新颖的跨学科培训计划，该计划整合了两个组成部分：1）NRSA 博士前培训计划和 2）短期研究教育计划，其中包括非 NRSA 博士前培训计划。体内成像技术取得了巨大进步，使神经科学家能够可视化分子、细胞和系统生理学和功能。为了充分利用神经影像技术，了解基本原理、数据检测、数据建模和可视化非常重要。此外，每种技术都有其自身的优点和局限性。为了克服一种神经成像方式的弱点，利用互补的成像方式是绝对必要的。通常，由于缺乏对这些方法的适当培训，研究人员可能不会利用先进的神经影像技术，因此，培训学生多种神经影像模式的原理和局限性至关重要。为了实现这一目标，我们建议为博士前和短期暑期学生创建多模态神经影像培训项目（T90/R90），该项目将由匹兹堡大学和卡内基梅隆大学联合运营。该项目将由认知神经基础中心 (CNBC) 管理，该中心无缝跨越两个机构，是一个具有国际地位的协调的跨学科研究和教育中心。博士前培训计划的具体目标是：1）教授综合神经影像研究的基础神经科学； 2) 教授从动物到人类的结构磁共振成像（MRI）、功能性磁共振成像、正电子发射断层扫描、脑磁图和光学成像的基本原理、建模和应用； 3）整合多种方法，开展多模态神经影像项目。为了实现具体目标，学员将参加核心课程和实验室轮转、研讨会并参加年度静修活动。除了研究生 T90/R90 培训计划外，短期多模态神经影像暑期学校 (R90) 还计划为在一种成像模式方面有经验并希望将培训扩展到其他模式的目标学生和研究人员教授多模式神经影像学的协同作用。夏季课程将包括基础讲座、实验室实践研讨会和表演项目，强调多种成像模式的方法。我们提出的计划将培训研究人员充分处理将多模态神经影像数据与各种数据采集和处理方法的知识以及适当的解释相结合的日益复杂性。这将加速多种成像模式在动物和人类基础和临床神经科学研究中的协同应用。所有培训教师都在有效的跨学科培训和合作研究方面拥有出色的记录。本培训计划中开发的材料将通过网络分发。