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EFFECTS OF BRAIN GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP)

EFFECTS OF BRAIN GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP)
脑葡萄糖依赖性促胰岛素多肽 (GIP) 的作用
批准号：
7957948
负责人：
ROBERT E SHADE
金额：
$1.39万
依托单位：
TEXAS BIOMEDICAL RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-06-06 至 2010-04-30
来源：
https://reporter.nih.gov/project-details/7957948
关键词：
BrainComputer Retrieval of Information on Scientific Projects DatabaseFundingGNAI2 geneGlucoseGrantHormonesInstitutionOralPapioPrimatesResearchResearch PersonnelResourcesRoleSignal TransductionSmall IntestinesSourceTestingUnited States National Institutes of Healthbody sensegastric inhibitory polypeptide receptorinsulin sensitivity

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will test the hypothesis that a recently discovered hormone synthesized by the small intestine, glucose-dependent insulinotropic polypeptide(GIP), has a role in brain signaling related to sensing body glucose availability. This will be done by estimating insulin sensitivity to an oral glucose challenge in baboons before and after chronically increasing brain GIP levels.
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EFFECTS OF BRAIN GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP)
OF LOWER BODY NEGATIVE PRESSURE AS A HYPOVOLEMIA MODEL IN BABOONS
NEUROSCIENCE CENTER FOR INGESTIVE BEHAVIOR
NEUROSCIENCE CENTER FOR INGESTIVE BEHAVIOR