NEUROSCIENCE CENTER FOR INGESTIVE BEHAVIOR

摄取行为神经科学中心

• 批准号: 7716034
• 负责人: ROBERT E SHADE
• 金额: $ 4.25万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7716034
• 关键词: Appetite Regulation; Appetitive Behavior; Behavior; Blood Pressure; Brain; Computer Retrieval of Information on Scientific Projects Database; Disease; Feeding behaviors; Funding; Grant; Human; Institution; Lead; Modeling; Neurosciences; Pan Genus; Pan troglodytes; Papio; Research; Research Personnel; Resources; Risk Factors; Sodium Chloride; Source; United States National Institutes of Health; Water consumption; mouse model; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ingestive behavior is a major factor in predisposing to a variety of diseases, but the neurohumoral mechanisms responsible for ingestive behavior are not well understood. An understanding of those mechanisms may lead to new strategies for controlling digestive behaviors that are risk factors for specific diseases. This is a multi-investigator program that involves several institutions. The objectives are to develop a better understanding of the following 1. Neurohumoral organization of ingestive behavior in a mouse model. 2. Salt-sensitivity of blood pressure in a chimpanzee model. 3.Brain regulation of appetite mechanisms in humans and in a baboon model. 4. Neurohumoral control of salt and water intake in a baboon model.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 摄食行为是诱发多种疾病的主要因素，但引起摄食行为的神经体液机制尚不清楚。 了解这些机制可能会导致控制消化行为的新策略，而消化行为是特定疾病的危险因素。 这是一个涉及多个机构的多研究者计划。 目的是更好地理解以下内容： 1. 小鼠模型中摄取行为的神经体液组织。 2. 黑猩猩模型中血压的盐敏感性。 3.人类和狒狒模型中食欲机制的大脑调节。 4. 狒狒模型中盐和水摄入的神经体液控制。