NEUROSCIENCE CENTER FOR INGESTIVE BEHAVIOR

摄取行为神经科学中心

• 批准号: 8357639
• 负责人: ROBERT E SHADE
• 金额: $ 24.89万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357639
• 关键词: Appetite Regulation; Behavior; Blood Pressure; Brain; Disease; Feeding behaviors; Funding; Grant; Human; Institution; Lead; Modeling; National Center for Research Resources; Neurosciences; Pan Genus; Papio; Primates; Principal Investigator; Research; Research Infrastructure; Research Personnel; Resources; Risk Factors; Sodium Chloride; Source; United States National Institutes of Health; Water consumption; cost; mouse model; programs; salt intake

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Ingestive behavior is a major factor in predisposing to a variety of diseases, but the neurohumoral mechanisms responsible for ingestive behavior are not well understood. An understanding of those mechanisms may lead to new strategies for controlling digestive behaviors that are risk factors for specific diseases. This is a multi-investigator program that involves several institutions. The objectives are to develop a better understanding of the following 1. Neurohumoral organization of ingestive behavior in a mouse model. 2. Salt-sensitivity of blood pressure in a chimpanzee model. 3.Brain regulation of appetite mechanisms in humans and in a baboon model. 4. Neurohumoral control of salt and water intake in a baboon model.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 摄食行为是诱发多种疾病的主要因素，但对摄食行为的神经体液机制还不清楚。 对这些机制的理解可能会导致控制消化行为的新策略，这些消化行为是特定疾病的危险因素。 这是一个涉及多个机构的多研究者计划。 目标是更好地理解以下内容1。小鼠模型摄食行为的神经体液组织。 2.黑猩猩血压的盐敏感性模型。 3.人类和狒狒模型中食欲机制的大脑调节。 4.狒狒模型中盐和水摄入的神经体液控制。