VIRTUAL CELL MODEL INTEROPERABILITY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. XML is used internally as an intermediate format (Virtual Cell Markup Language) for lightweight persistence (greatly increasing model load performance), client-side caching, and to provide language and platform independent communication. The Systems Biology Markup Language (SBML) allows a level of model interoperability among the existing modeling tools and model repositories and is actively supported by the Virtual Cell, both by contributing to the standard and by importing and exporting compliant models. Support for importing and exporting models in the CellML format has been provided and requires periodic maintenance. Other interoperability standards will be considered in the future.