Diet, lifestyle and biological determinants of health and chronic diseases: the EPIC-Norfolk Prospective population study

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As the population ages, a major challenge is how we can maintain good health and prevent disease and disability. EPIC-Norfolk(European Prospective Investigation into Cancer in Norfolk) is a study of 25,000 men and women aged 40-79 years living in East Anglia who contributed detailed information on their health and lifestyle, in particular, diet and physical activity in 1993-1997 and who have since been followed up to examine what factors predict health as we age. This study aims to understand better how to prevent and treat many of the chronic diseases associated with ageing such as heart disease and stroke, cancer, arthritis, diabetes, respiratory disease and osteoporosis leading to fractures as well as how to maintain optimal health in later life. Measurements of new biologic markers in blood, including genetic profile, are also enabling us to understand better disease processes and progression, which may help us identify better treatments. We continuing to follow up the participants in this study and in the next phase, assess physical and mental function to examine how we can influence how these change as we age.