Diet, lifestyle and biological determinants of health and chronic diseases: the EPIC-Norfolk Prospective population study

饮食、生活方式以及健康和慢性病的生物决定因素：EPIC-诺福克前瞻性人口研究

• 批准号: G0401527/1
• 负责人: Kay-Tee Khaw
• 金额: $ 273.63万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0401527%2F1
• 关键词: Diet; lifestyle; biological; determinants; health

As the population ages, a major challenge is how we can maintain good health and prevent disease and disability. EPIC-Norfolk(European Prospective Investigation into Cancer in Norfolk) is a study of 25,000 men and women aged 40-79 years living in East Anglia who contributed detailed information on their health and lifestyle, in particular, diet and physical activity in 1993-1997 and who have since been followed up to examine what factors predict health as we age. This study aims to understand better how to prevent and treat many of the chronic diseases associated with ageing such as heart disease and stroke, cancer, arthritis, diabetes, respiratory disease and osteoporosis leading to fractures as well as how to maintain optimal health in later life. Measurements of new biologic markers in blood, including genetic profile, are also enabling us to understand better disease processes and progression, which may help us identify better treatments. We continuing to follow up the participants in this study and in the next phase, assess physical and mental function to examine how we can influence how these change as we age.

随着人口老龄化，一个重大挑战是我们如何保持良好的健康和预防疾病和残疾。EPIC-诺福克（欧洲诺福克癌症前瞻性调查）是一项对居住在东安格利亚的25，000名年龄在40-79岁的男性和女性的研究，他们在1993-1997年提供了关于他们的健康和生活方式的详细信息，特别是饮食和体育活动，并从那时起进行了随访，以检查随着年龄的增长，哪些因素可以预测健康。这项研究旨在更好地了解如何预防和治疗许多与衰老相关的慢性疾病，如心脏病和中风，癌症，关节炎，糖尿病，呼吸系统疾病和导致骨折的骨质疏松症，以及如何在晚年保持最佳健康。血液中新生物标志物的测量，包括遗传特征，也使我们能够更好地了解疾病的过程和进展，这可能有助于我们确定更好的治疗方法。我们将继续跟踪这项研究的参与者，并在下一阶段评估身体和精神功能，以研究我们如何影响这些功能随着年龄的增长而发生的变化。