Patient motion sensing in nuclear medicine scans

核医学扫描中的患者运动传感

• 批准号: 7690062
• 负责人: FRANK P DIFILIPPO
• 金额: $ 7.85万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7690062
• 关键词: Affect; Algorithms; Brain; Cardiac; Characteristics; Clinical; Clinical Research; Computer software; Data; Devices; Discipline of Nuclear Medicine; Effectiveness; Electronics; Encapsulated; Financial compensation; Freedom; Frequencies; Future; Goals; Image; Kidney; Laboratory Research; Location; Measurement; Measures; Motion; Nature; Noise; Nuclear; Optics; Patients; Performance; Physicians; Pilot Projects; Positioning Attribute; Positron-Emission Tomography; Process; Radionuclide Imaging; Reading; Research; Research Project Grants; Rotation; Scanning; Source; System; Techniques; Technology; Testing; Time; Training; Vision; Walking; Weight; Wireless Technology; Work; base; clinical application; computerized data processing; cost; design; millimeter; novel; novel strategies; prevent; public health relevance; reconstruction; sensor; single photon emission computed tomography

DESCRIPTION (provided by applicant): Patient motion is a major issue in nuclear medicine imaging studies, which require substantial time to acquire enough counts to produce clinical-quality images. Motion correction algorithms exist but have limited accuracy and effectiveness, and in many instances the only practical alternative is to re-scan the patient. Most work on patient motion sensing has focused on optical tracking systems mainly for brain PET studies. Although sub- millimeter accuracy has been attained in research laboratories, the cost, complexity, and line-of-sight requirement of external optical tracking systems have prevented their routine use in clinical nuclear medicine departments. There is an unmet clinical need for a practical and affordable patient motion sensing device for general nuclear medicine studies. A high level of accuracy is welcome but not critical. For example, merely being able to detect large shifts and rotations in real time during a scan would be helpful to a technologist deciding whether to re-scan a patient. Information on the timing and magnitude of patient motion also would be helpful during data processing and image interpretation. We therefore propose a novel low-cost patient motion sensor that, although not having the same level of accuracy as optical tracking systems, is expected to have sufficient performance to benefit nuclear medicine studies. In this research project we will perform a pilot study to evaluate the feasibility of the motion sensing device in a clinical setting and to assess its impact to the technologist and physician. Based on the results of this pilot study, we envision developing and testing advanced versions of the device optimized for specific clinical applications. PUBLIC HEALTH RELEVANCE: We propose to evaluate the performance and potential impact of a novel patient motion sensing device for clinical nuclear medicine studies. Patient motion often limits image quality, and there is an unmet clinical need for a low-cost motion sensor that is practical for clinical nuclear medicine departments. The data from this pilot study will determine the feasibility of the device and will guide future research in technology improvements and clinical applications.

描述（由申请人提供）：患者运动是核医学成像研究中的一个主要问题，需要大量时间来获取足够的计数以生成临床质量的图像。存在运动校正算法，但其准确性和有效性有限，并且在许多情况下，唯一实际的替代方案是重新扫描患者。关于患者运动感测的大多数工作集中在主要用于脑PET研究的光学跟踪系统上。虽然在研究实验室中已经达到亚毫米精度，但是外部光学跟踪系统的成本、复杂性和视线要求已经阻止了它们在临床核医学部门中的常规使用。对于用于一般核医学研究的实用且负担得起的患者运动感测设备存在未满足的临床需求。高水平的准确性是受欢迎的，但不是关键的。例如，仅仅能够在扫描期间在真实的时间内检测大的移位和旋转将有助于技术专家决定是否重新扫描患者。在数据处理和图像解释期间，关于患者运动的时间和幅度的信息也将是有帮助的。因此，我们提出了一种新的低成本的患者运动传感器，虽然不具有相同的精度水平的光学跟踪系统，预计将有足够的性能，有利于核医学研究。在本研究项目中，我们将进行一项试点研究，以评估运动传感设备在临床环境中的可行性，并评估其对技术人员和医生的影响。根据这项试点研究的结果，我们设想开发和测试针对特定临床应用优化的先进版本的设备。公共卫生关系：我们建议评估一种新型患者运动传感设备的性能和潜在影响，用于临床核医学研究。患者运动通常限制图像质量，并且存在对于临床核医学部门实用的低成本运动传感器的未满足的临床需求。这项初步研究的数据将确定该设备的可行性，并将指导未来的技术改进和临床应用研究。