Patient motion sensing in nuclear medicine scans

核医学扫描中的患者运动传感

• 批准号: 7894823
• 负责人: FRANK P DIFILIPPO
• 金额: $ 7.85万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7894823
• 关键词: Affect; Algorithms; Brain; Cardiac; Characteristics; Clinical; Clinical Research; Computer software; Data; Devices; Discipline of Nuclear Medicine; Effectiveness; Electronics; Encapsulated; Financial compensation; Freedom; Frequencies; Future; Goals; Image; Kidney; Laboratory Research; Location; Measurement; Measures; Motion; Nature; Noise; Nuclear; Optics; Patients; Performance; Physicians; Pilot Projects; Positioning Attribute; Positron-Emission Tomography; Process; Radionuclide Imaging; Reading; Research; Research Project Grants; Rotation; Scanning; Source; System; Techniques; Technology; Testing; Time; Training; Vision; Walking; Weight; Wireless Technology; Work; base; clinical application; computerized data processing; cost; design; millimeter; novel; novel strategies; prevent; public health relevance; reconstruction; sensor; single photon emission computed tomography

DESCRIPTION (provided by applicant): Patient motion is a major issue in nuclear medicine imaging studies, which require substantial time to acquire enough counts to produce clinical-quality images. Motion correction algorithms exist but have limited accuracy and effectiveness, and in many instances the only practical alternative is to re-scan the patient. Most work on patient motion sensing has focused on optical tracking systems mainly for brain PET studies. Although sub- millimeter accuracy has been attained in research laboratories, the cost, complexity, and line-of-sight requirement of external optical tracking systems have prevented their routine use in clinical nuclear medicine departments. There is an unmet clinical need for a practical and affordable patient motion sensing device for general nuclear medicine studies. A high level of accuracy is welcome but not critical. For example, merely being able to detect large shifts and rotations in real time during a scan would be helpful to a technologist deciding whether to re-scan a patient. Information on the timing and magnitude of patient motion also would be helpful during data processing and image interpretation. We therefore propose a novel low-cost patient motion sensor that, although not having the same level of accuracy as optical tracking systems, is expected to have sufficient performance to benefit nuclear medicine studies. In this research project we will perform a pilot study to evaluate the feasibility of the motion sensing device in a clinical setting and to assess its impact to the technologist and physician. Based on the results of this pilot study, we envision developing and testing advanced versions of the device optimized for specific clinical applications. PUBLIC HEALTH RELEVANCE: We propose to evaluate the performance and potential impact of a novel patient motion sensing device for clinical nuclear medicine studies. Patient motion often limits image quality, and there is an unmet clinical need for a low-cost motion sensor that is practical for clinical nuclear medicine departments. The data from this pilot study will determine the feasibility of the device and will guide future research in technology improvements and clinical applications.

描述(由申请人提供)：患者运动是核医学成像研究中的一个主要问题，这需要大量的时间来获得足够的计数来产生临床质量的图像。运动矫正算法已经存在，但其准确性和有效性有限，在许多情况下，唯一可行的替代方案是重新扫描患者。大多数关于患者运动感知的工作主要集中在光学跟踪系统上，主要用于脑PET研究。尽管研究实验室已经达到了亚毫米级的精度，但外部光学跟踪系统的成本、复杂性和视距要求阻碍了它们在临床核医学科中的常规使用。临床上对用于一般核医学研究的实用且负担得起的患者运动传感设备的需求尚未得到满足。高水平的准确性是受欢迎的，但不是关键。例如，仅仅是能够在扫描过程中实时检测到大的位移和旋转就可以帮助技术专家决定是否重新扫描患者。在数据处理和图像解释过程中，有关患者运动的时间和大小的信息也将有所帮助。因此，我们提出了一种新型的低成本患者运动传感器，虽然没有光学跟踪系统的精度，但有望具有足够的性能来促进核医学研究。在这个研究项目中，我们将进行一项初步研究，以评估运动传感设备在临床环境中的可行性，并评估其对技术人员和医生的影响。根据这项初步研究的结果，我们预计将开发和测试针对特定临床应用而优化的设备的高级版本。公共卫生相关性：我们建议评估一种用于临床核医学研究的新型患者运动传感设备的性能和潜在影响。患者的运动往往会限制图像质量，临床上对低成本运动传感器的需求还没有得到满足，这种传感器适用于临床核医学部门。这项先导性研究的数据将确定该设备的可行性，并将指导未来的技术改进和临床应用研究。