Identifying key players in the spread of antimicrobial resistance

确定抗菌素耐药性传播的关键参与者

• 批准号: nhmrc : 1043830
• 负责人: A/Pr Kathryn Holt
• 金额: $ 54.51万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-key-players-antimicrobial-resistance/111607
• 关键词: Identifying; key; players; spread; antimicrobial

Antibiotic drugs are essential to treat bacterial infections. However some bacteria have genes that allow them to resist certain drugs, which can be transferred among bacteria to create 'superbugs' that can resist nearly all the drugs we have. This project investigates the transfer of drug resistance genes between Gram negative bacteria (common agents of food poisoning, hospital infection, UTI, etc) and aims to identify the bacteria and genes most important in the spread of superbugs in Australia.

抗生素药物是治疗细菌感染的必要药物。然而，一些细菌具有使它们能够抵抗某些药物的基因，这些基因可以在细菌之间转移，从而产生可以抵抗我们拥有的几乎所有药物的“超级细菌”。该项目调查了革兰氏阴性菌（食物中毒，医院感染，UTI等的常见病原体）之间的耐药基因转移，旨在确定在澳大利亚超级细菌传播中最重要的细菌和基因。