Bacterial population genomics and human disease

细菌群体基因组学和人类疾病

• 批准号: nhmrc : GNT1061409
• 负责人: A/Pr Kathryn Holt
• 金额: $ 40.49万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/bacterial-population-genomics-human-disease/1344767
• 关键词: Bacterial; population; genomics; human; disease

DNA sequencing allows us to see into the microbial world in fine detail. This enables us to investigate how bugs like bacteria cause infections and other diseases. In this fellowship, I will use DNA sequencing and analysis to investigate how bacterial infections are transmitted in hospitals and cities, how bacteria become resistant to the antibiotic drugs we use to treat infected people, and how the bacteria that live in our nose and throat contribute to development of asthma in young children.

DNA测序使我们能够看到微生物世界的细节。这使我们能够研究细菌等细菌是如何引起感染和其他疾病的。在这项研究中，我将使用DNA测序和分析来调查细菌感染是如何在医院和城市传播的，细菌是如何对我们用来治疗感染者的抗生素药物产生抗药性的，以及生活在我们鼻子和喉咙中的细菌是如何导致幼儿哮喘的发展的。