Diabetes Endocrinology Research Center (DERC)

糖尿病内分泌研究中心（DERC）

• 批准号: 7619910
• 负责人: David Marshall Harlan
• 金额: $ 141.28万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7619910
• 关键词: Diabetes; Endocrinology; Research; Center; DERC

The University of Massachusetts Medical School Diabetes and Endocrinology Research Center was established in 1982 with the goal of enhancing and promoting research in diabetes and related metabolic and endocrine disorders. During its 22 years of activity, it has brought together an expanding, multidisciplinary group of nearly 60 independent member scientists, new investigators, and research trainees who represent nearly all disciplines of Medicine and the Basic Sciences. The DERC has fostered a successful enrichment program and both small and large scale collaborations, including several interdisciplinary Program Projects. The DERC has also formally integrated Staff Scientists from The Jackson Laboratory into its research base and administrative structure. The Commonwealth of Massachusetts has reciprocated with support for interdisciplinary programs and capital investments in research facilities the scope of DERC-supported research activities is very broad, ranging from basic molecular biology to clinical tolerance-based transplantation in diabetic patients. All members, however, share a common interest in research that is fundamental to understanding diabetes pathogenesis, is directed towards the development of new treatment strategies, or is focused on related metabolic and endocrine disorders. The DERC is designed to maintain and to enhance an infrastructure that has already demonstrated its ability to catalyze innovative research. The focus of the DERC remains its Research Cores, which are now be expanded to eight in number to make available required cutting edge technologies. The Cores provide funded basic and clinical investigators with the opportunity to utilize resources efficiently and to expand the scope of their research programs. These include Flow Microfluorometry, Tissue Culture, Transgenic Animals, Genomics, Morphology, Electron Microscopy, Cell Imaging, and Proteomics Cores. An Administrative Core oversees the operation of the Center, Pilot and Feasibility Projects, and the Enrichment Programs. The goal of the University of Massachusetts Medical School DERC has been and will continue to be to facilitate research in diabetes and related subjects. Specifically, the DERC will 1) stimulate interdisciplinary interactions 2) efficiently enhance the productivity and efficiency of diabetes research through Core facilities, 3) bootstrap new research efforts through pilot and feasibility awards, 4) promote the training of young investigators in diabetes-related research, and 5) create an institution environment that amplifies research efforts in diabetes or related metabolic and endocrine disorders.

马萨诸塞大学医学院糖尿病和内分泌研究中心成立于1982年，旨在加强和促进糖尿病及相关代谢和内分泌疾病的研究。在其22年的活动中，它汇集了一个不断扩大的多学科小组，由近60名独立成员科学家、新的研究人员和研究实习生组成，他们几乎代表了医学和基础科学的所有学科。DERC促进了一个成功的浓缩计划以及小规模和大规模的合作，包括几个跨学科计划项目。DERC还正式将杰克逊实验室的工作人员科学家纳入其研究基地和行政结构。马萨诸塞州联邦对跨学科项目和研究设施的资本投资给予了回报。DERC支持的研究活动范围非常广泛，从基础分子生物学到 糖尿病患者的临床耐受性移植。然而，所有成员都有一个共同的兴趣，即对了解糖尿病发病机制至关重要的研究，针对新治疗策略的开发，或专注于相关代谢和内分泌疾病的研究。DERC旨在维护和加强已经证明其有能力催化创新研究的基础设施。DERC的重点仍然是其研究核心，现已扩大到8个，以提供所需的尖端技术。这些核心为受资助的基础和临床研究人员提供了有效利用资源和扩大其研究计划范围的机会。这些技术包括流动显微荧光法、组织培养、 转基因动物，基因组学，形态学，电子显微镜，细胞成像，蛋白质组学核心。一个行政核心监督该中心、试点和可行性项目以及浓缩项目的运作。马萨诸塞大学医学院DERC的目标一直是，并将继续促进糖尿病和相关学科的研究。具体地说，DERC将1)促进跨学科互动2)通过核心设施有效提高糖尿病研究的生产力和效率，3)通过试点和可行性奖引导新的研究努力，4)促进年轻研究人员在糖尿病相关研究方面的培训，以及5)创造一个机构环境，扩大糖尿病或相关代谢和内分泌疾病的研究努力。