SYMPATHETIC RESPONSES TO PERIPHERAL VASCULAR DISTENTION IN SKELETAL MUSCLES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本初步研究的目的是检查骨骼肌静脉血管扩张时心血管和交感神经的反应。据推测，外周血管扩张可能引起交感神经激活，诱导升压反应（B. P.和H.R.增加）。在人类身上。 在各种条件下，静脉输注生理盐水将产生静脉扩张，肌肉交感神经活动（MSNA）将反映在B. P和H. R中。变化假设外周静脉扩张会引起MSNA增加。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this pilot study is to examine the cardiovascular and sympathetic responses to venous vascular distention in skeletal muscles. It is postulated that peripheral vascular distention may evoke sympathetic activation, inducing a pressor response (Increased B.P. and H.R.) in humans. Venous distention will be produced by intravenous saline infusion under various conditions and the muscle sympathetic neural activity (MSNA) will be reflected in B.P. and H.R. changes. The hypothesis is that peripheral venous distention will evoke an increase in MSNA.