THE EFFECTS OF MELATONIN ON THE VESTIBULOSYMPATHETIC REFLEX

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究旨在探讨褪黑素对前庭交感神经反射的影响。将测试以下假设：褪黑激素将导致前庭交感神经反射的MSNA衰减;在施用褪黑激素后，对主要动脉床的血管反应（即，前臂、小腿、肾脏、冠状动脉等）在前庭交感神经反射的激活过程中会减弱。褪黑激素对女性的前庭交感神经反射的影响大于男性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to investigate the effects of melatonin on the vestibulosympathetic reflex. The following hypotheses will be tested: melatonin will cause attenuation in MSNA of the vestibulosympathetic reflex; following the administration of melatonin, vascular responses to major arterial beds (i.e., forearm, calf, renal, coronary, etc.) will be attenuated during activation of the vestibulosympathetic reflex.; and melatonin will have a greater effect on the vestibulosympathetic reflex in women than men.