CLINICAL TRIAL: A NOVEL THERAPY FOR GLUCOSE INTOLERANCE IN HIV DISEASE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 本研究旨在探讨吡啶甲酸铬的营养补充剂。大量的人使用从健康食品商店吡啶甲酸铬，以改善功能的激素胰岛素。我们正在测试这种补充剂的有效性，我们也在监测其安全性。由于艾滋病病毒的多药治疗可引起胰岛素不敏感或抵抗，我们正在研究有胰岛素抵抗记录的艾滋病病毒阳性个体。在糖尿病患者中，铬已被证明可以增加对激素胰岛素的敏感性。我们想知道铬是否也能有效治疗与艾滋病相关的耐药性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research is to investigate the nutritional supplement chromium picolinate. A large number of people use chromium picolinate from health food stores to improve function of the hormone insulin. We are testing how effective this supplement is and we are also monitoring its safety. SInce multidrug treatment for HIV can cause insensitivity or resistance to insulin, we are studying HIV positive individulas with documented insulin resistance. In patients with diabetes, chromium has been shown to increase sensitivity to the hormone insulin. We would like to know if chromium is also effective in treating resistance associated with HIV disease.