CLINICAL TRIAL: A NOVEL THERAPY FOR GLUCOSE INTOLERANCE IN HIV DISEASE

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究旨在探讨营养补充剂吡啶甲酸铬。许多人使用保健食品商店的吡啶甲酸铬来改善激素胰岛素的功能。我们正在测试这种补充剂的有效性，并监测其安全性。由于艾滋病毒的多种药物治疗可能导致胰岛素不敏感或抵抗，因此我们正在研究有记录的胰岛素抵抗的艾滋病毒阳性个体。在糖尿病患者中，铬已被证明可以增加对胰岛素激素的敏感性。我们想知道铬是否也能有效治疗与艾滋病毒相关的耐药性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research is to investigate the nutritional supplement chromium picolinate. A large number of people use chromium picolinate from health food stores to improve function of the hormone insulin. We are testing how effective this supplement is and we are also monitoring its safety. SInce multidrug treatment for HIV can cause insensitivity or resistance to insulin, we are studying HIV positive individulas with documented insulin resistance. In patients with diabetes, chromium has been shown to increase sensitivity to the hormone insulin. We would like to know if chromium is also effective in treating resistance associated with HIV disease.