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STRUCTURE OF A REGULATORY PROTEIN-LIKE PROTEIN

STRUCTURE OF A REGULATORY PROTEIN-LIKE PROTEIN
调节蛋白样蛋白质的结构
批准号：
7954301
负责人：
IRIMPAN I MATHEWS
金额：
$0.19万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-03-01 至 2010-02-28
来源：
https://reporter.nih.gov/project-details/7954301
关键词：
CellsComputer Retrieval of Information on Scientific Projects DatabaseCrystallizationFundingGrantInstitutionProteinsResearchResearch PersonnelResourcesSourceStructureUnited States National Institutes of Healthgenetic regulatory proteinmutantresearch studystructural biologysynchrotron radiation

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protein has some sequence similarity to thioesterase. We have crystallized the protein under two different conditions. The crystals diffract to ~5 A with a very large unit cell. Therefore, further crystallization experiments are in progress to generated different crystallization conditions. Studies are also planned with different substrates and a number of mutants.
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