Biology of Infectious Diseases Training Program

传染病生物学培训计划

• 批准号: 8101963
• 负责人: Henry F HENRY CHAMBERS
• 金额: $ 20.71万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8101963
• 关键词: Biology; Communicable Diseases; Training Programs

DESCRIPTION (provided by applicant): This is a second revised application for competitive renewal for the UCSF Biology of Infectious Diseases Training Program to train physician-scientists for productive careers in fundamental scientific investigations of infectious diseases. Infectious diseases are the third most common cause of death in the United States, despite widespread availability of antibiotics, vaccines, and high standards of public health. Worldwide, infectious diseases are the leading cause of death. Emergence of new pathogens, re-emergence of old ones, increasing resistance to antimicrobials, and pressures of globalization have broken down barriers and contributed to the spread of infectious diseases. Strategies to contain and control the spread of infectious diseases increasingly will rely on strong epidemiologic and population-based approaches and advances in basic research resulting from applications of discoveries in the fields of genomics, microbial pathogenesis, and immunology. The UCSF Biology of Infectious Diseases Training Program, which is modeled according to Infectious Diseases Society of America guidelines and recommendations, features two training tracks, a Basic Investigator Track and a Clinical Investigator Track. These two tracks provide the structural framework for acquisition and translation of research tools, skills, and experiences and for cultivating the scientific creativity that are essential for a successful research-oriented career. The two-track structure also affords the opportunity for interdisciplinary exchange and interactions. The program benefits from a well-established didactic infrastructure and an interactive faculty who direct research programs offering a rich and diversified training environment of exceptional depth and quality. Training is focused on MD and MD-PhD applicants, but PhD post-doctoral candidates are also accepted. In existence for only five years, the program has had considerable success in transitioning trainees to independent sources of research funding and starting them on promising career trajectories. This revised application features an innovative plan to recruit underrepresented minority trainees into the program; viewed as the weakness of the previous version, we believe this plan represents a major strength of the revised proposal. Relevance: The proposed training program is highly relevant to public health, a major concern of which is the control of infectious diseases. We will be training the next generation of medical scientists who will have responsibility for public health and devising strategies to contain the threats posed by infectious agents, scientists who will conduct the studies needed to identify new agents, and those who will discover approaches and therapies to overcome them.

描述（由申请人提供）：这是对UCSF传染病培训计划生物学竞争更新的第二次修订申请，以培训医生 - 科学家从事生产力职业，从而在传染病的基本科学研究中进行生产力。尽管抗生素，疫苗和高标准的公共卫生标准广泛可用，但传染病是美国第三大常见的死亡原因。在全球范围内，传染病是死亡的主要原因。新病原体的出现，旧病原体的重新出现，对抗菌剂的抗药性增加以及全球化的压力破坏了障碍，并导致了传染病的传播。越来越多的策略遏制和控制传染性疾病的传播将依赖于强烈的流行病学和基于人群的方法以及基础研究的进步，这是由于在基因组学领域的应用，微生物发病机理和免疫学领域的应用而导致的。 UCSF传染病培训计划的生物学，该计划是根据传染病学会指南和建议进行建模的，具有两个培训轨道，基本的研究者轨道和临床研究者轨道。这两个曲目为研究工具，技能和经验的获取和翻译提供了结构性框架，并培养了成功以研究为导向的职业至关重要的科学创造力。两轨结构还为跨学科交流和互动提供了机会。该计划受益于建立完善的教学基础设施和一个互动教师，他们指导研究计划提供丰富而多元化的培训环境，具有卓越的深度和质量。培训集中在MD和MD-PHD申请人上，但博士学位后候选人也被接受。该计划仅五年了，在将学员转变为独立的研究资金来源，并以有前途的职业轨迹开始，该计划取得了巨大的成功。该修订的应用程序具有创新的计划，旨在招募代表性不足的少数族裔学员加入该计划；我们认为该计划被视为以前版本的弱点，这是修订建议的主要优势。相关性：拟议的培训计划与公共卫生高度相关，主要关注的是控制传染病。我们将培训下一代的医学科学家，他们将对公共卫生负责，并制定策略来控制传染性特工，科学家，他们将进行所需的研究以识别新特工，以及那些将发现方法和疗法以克服它们的方法。