HORIZON Center: Healthy Options, Research, Interventions & Community Organizing

HORIZON 中心：健康选择、研究、干预措施

• 批准号: 8077401
• 负责人: CELIA L. MOORE
• 金额: $ 106.04万
• 依托单位: UNIVERSITY OF MASSACHUSETTS BOSTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8077401
• 关键词: HORIZON; Center; Healthy; Options; Research

DESCRIPTION (provided by applicant): University of Massachusetts Boston (UMass Boston) and Harvard University School of Public Health (HSPH) have partnered with the Cherishing Our Hearts and Souls Coalition (COHS) of Roxbury (a Boston neighborhood comprised of 51% African Americans and 23% Hispanics) to establish an exploratory Center (P20) for Health and Health Care Disparities that is dedicated to Community Based Participatory Research (CBPR). The Healthy Options, Research, Interventions & Community Organizing Center (HORIZON Center) will: 1) conduct health disparities related research projects in partnership with COHS, 2) offer research training, with an emphasis in CBPR, to faculty, students, and community stakeholders, and 3) build a neighborhood based infrastructure that can partner with academic institutions in Boston to research and implement "best practices" in CBPR and academic-community partnerships. UMass Boston was designated a minority-serving institution by the National Cancer Institute and is the lead partner in the HORIZON Center. The diverse characteristics and strengths reflected in both academic institutions and in the six-year old community coalition (COHS) set the stage for significant changes in cultural norms (public knowledge, attitudes and behaviors) and professional practices surrounding research activities and academic community partnerships. The implications of successfully engaging a diverse urban underserved community in health promotion activities, in research and in advancing the cause of research are nationally significant. We partner to further the research mission of COHS and its Community Research Advisory Board (CRAB). The HORIZON Center has 4 cores, 3 research projects and 6 pilot projects; all designed to strengthen the evidence-based practices and strategies for understanding and training practitioners in health disparities reduction. We propose to increase the number of local agencies, community organizations and residents that contribute to and participate in research, training, health promotion, and community organizing activities. The cores provide an infrastructure and process for the translation of research into innovative community outreach strategies, educational interventions and public policy initiatives. The Administrative Core provides overall support to the HORIZON Center by coordinating the other cores and projects. The Research Core supports the research projects which are investigating the behavioral, social, and biological sciences related to health disparities. The Community Engagement Core is responsible for projects that investigate the best practices for outreach and mobilization in an urban community. The Training Core is responsible for projects that implement and evaluate strategies for increasing the number of people who are trained and engaged in CBPR and from health disparity populations.

描述(由申请人提供)：马萨诸塞大学波士顿分校(UMassBoston)和哈佛大学公共卫生学院(HSPH)与罗克斯伯里(Roxbury)珍爱我们的心灵和灵魂联盟(Cohs)(波士顿社区，51%的非裔美国人和23%的西班牙裔美国人)合作，建立了一个卫生和医疗保健差距探索中心(P20)，致力于基于社区的参与性研究(CBPR)。健康选择、研究、干预和社区组织中心(Horizon Center)将：1)与CoHS合作开展与健康差距相关的研究项目；2)向教职员工、学生和社区利益相关者提供研究培训，重点是CBPR；3)建立一个社区基础设施，可以与波士顿的学术机构合作，研究和实施CBPR和学术-社区合作伙伴关系中的“最佳实践”。马萨诸塞州大学波士顿分校被国家癌症研究所指定为少数族裔服务机构，是地平线中心的主要合作伙伴。两个学术机构和成立六年的社区联盟(COHS)所反映的不同特点和优势为围绕研究活动和学术界伙伴关系的文化规范(公共知识、态度和行为)和专业做法的重大变化奠定了基础。成功地让一个多样化的、服务不足的城市社区参与健康促进活动、研究和推进研究事业的意义在全国具有重要意义。我们与COHS及其社区研究咨询委员会(CRAB)合作，推动其研究使命的实现。地平线中心有4个核心、3个研究项目和6个试点项目；所有这些项目都是为了加强循证做法和战略，以了解和培训从业人员缩小健康差距。我们建议增加有助于和参与研究、培训、健康促进和社区组织活动的当地机构、社区组织和居民的数量。这些核心为将研究转化为创新的社区外联战略、教育干预措施和公共政策倡议提供了基础设施和程序。行政核心通过协调其他核心和项目为地平线中心提供全面支持。研究核心支持正在调查与健康差距有关的行为、社会和生物科学的研究项目。社区参与核心负责调查城市社区外展和动员的最佳做法的项目。培训核心负责实施和评估战略，以增加接受培训和参与CBPR的人数以及来自健康差距人口的人数。

项目成果

5-HT1A and α2 adrenergic receptor levels are associated with high anxiety-like patterns and impulsivity in selectively bred Long Evans rats.

5-HT1A 和α2 肾上腺素能受体水平与选择性繁殖的长埃文斯大鼠的高度焦虑样模式和冲动相关。

• DOI: 10.1016/j.bbr.2020.112522
• 发表时间: 2020
• 期刊: Behavioural brain research
• 影响因子: 2.7
• 作者: Niedzielak,Tim;Ravenelle,Rebecca;Joseph,Marie;Calhoun,Corey;Plotkin,Brooke;Jones,Raquel;Herrera,Maria;TiffanyDonaldson,S
• 通讯作者: TiffanyDonaldson,S

Periodic maternal deprivation may modulate offspring anxiety-like behavior through mechanisms involving neuroplasticity in the amygdala.

• DOI: 10.1016/j.brainresbull.2013.12.005
• 发表时间: 2014-02
• 期刊: Brain research bulletin
• 影响因子: 3.8
• 作者: Berman AK;Lott RB;Donaldson ST
• 通讯作者: Donaldson ST

Sex matters: females in proestrus show greater diazepam anxiolysis and brain-derived neurotrophin factor- and parvalbumin-positive neurons than males.

• DOI: 10.1111/ejn.13870
• 发表时间: 2018-04
• 期刊: The European journal of neuroscience
• 作者: Ravenelle R;Berman AK;La J;Mason B;Asumadu E;Yelleswarapu C;Donaldson ST
• 通讯作者: Donaldson ST

Pathways to service receipt: modeling parent help-seeking for childhood mental health problems.

• DOI: 10.1007/s10488-013-0484-6
• 发表时间: 2014-07
• 期刊: ADMINISTRATION AND POLICY IN MENTAL HEALTH AND MENTAL HEALTH SERVICES RESEARCH
• 影响因子: 2.6
• 作者: Godoy, Leandra;Mian, Nicholas D.;Eisenhower, Abbey S.;Carter, Alice S.
• 通讯作者: Carter, Alice S.

Housing environment modulates physiological and behavioral responses to anxiogenic stimuli in trait anxiety male rats.

• DOI: 10.1016/j.neuroscience.2014.03.060
• 发表时间: 2014-06-13
• 期刊: Neuroscience
• 影响因子: 3.3
• 作者: Ravenelle R;Santolucito HB;Byrnes EM;Byrnes JJ;Donaldson ST
• 通讯作者: Donaldson ST