Center of Excellence for Diabetes in Americans of Mexican Descent

墨西哥裔美国人糖尿病卓越中心

• 批准号: 8078122
• 负责人: JOSEPH MCCORMICK
• 金额: $ 139.91万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-03 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8078122
• 关键词: Center; Excellence; Diabetes; Americans; Mexican

DESCRIPTION (provided by applicant): Slowing the rate of increase in type 2 diabetes nationally is one of the most urgent health problems we face. Worst affected are minority populations such as the Mexican American population along the US/Mexico border, where rates have doubled over the last two decades (now over 20% of all adults). Even in children we find rates much higher than nationally of overweight and other predictors of early onset type 2 diabetes. The rate of increase shows no sign of slowing. It is difficult, therefore, to overstate the urgency of addressing effective measures to prevent diabetes in minority populations. This proposal builds on the research opportunities established in the Hispanic Health Research Center of the Lower Rio Grande Valley through NCMHD Project EXPORT (MD000170 P20). This Center of Excellence application aims to 1) understand the changes proximal to the development of overt diabetes, 2) understand the mental health impact of diabetes and the potential for early intervention, 3) utilize the strong family unit in the Mexican American population to reduce the risk of obesity and diabetes in children through parental intervention, and 4) understand how to use the successful technique of behavioral journalism and the media to change diet and physical activity behavior at the population level. The scientific focus of the Center of Excellence is thus to conduct research on the physiologic progression to diabetes and its complications among Mexican Americans, and to develop diabetes prevention strategies and test innovative approaches to effective interventions in a minority population severely affected by type 2 diabetes. We intend our Center of Excellence to be a collaborative resource for diabetes and its complications in Mexican Americans providing critical cultural understanding and appropriate tools for epidemiological, intervention, and physiologic research. The proposed Center of Excellence on Diabetes in Americans of Mexican Descent proposes an administrative core, a research core including three research projects and two pilot studies, a training core and a community engagement core.

描述（由申请人提供）：减缓全国2型糖尿病的增长速度是我们面临的最紧迫的健康问题之一。受影响最严重的是少数民族，如沿着美国/墨西哥边境的墨西哥裔美国人，在过去的二十年里，他们的发病率翻了一番（现在占所有成年人的20%以上）。即使在儿童中，我们也发现超重率和早发性2型糖尿病的其他预测因素远高于全国水平。增长速度没有放缓的迹象。因此，很难夸大采取有效措施预防少数群体糖尿病的紧迫性。本提案基于通过NCMHD项目出口（MD 000170 P20）在下格兰德河谷西班牙裔健康研究中心建立的研究机会。该卓越中心的应用旨在1）了解显性糖尿病发展的近端变化，2）了解糖尿病对心理健康的影响和早期干预的潜力，3）利用强大的 家庭单位在墨西哥裔美国人的人口，以减少肥胖和糖尿病的风险，在儿童通过父母的干预，和4）了解如何使用成功的技术，行为新闻和媒体，以改变饮食和体育活动的行为，在人口水平。因此，卓越中心的科学重点是对墨西哥裔美国人糖尿病及其并发症的生理进展进行研究，并制定糖尿病预防策略，并测试在严重受2型糖尿病影响的少数人群中进行有效干预的创新方法。我们希望我们的卓越中心成为墨西哥裔美国人糖尿病及其并发症的协作资源，为流行病学，干预和生理研究提供关键的文化理解和适当的工具。拟议的墨西哥裔美国人糖尿病卓越中心提出了一个行政核心，一个研究核心，包括三个研究项目和两个试点研究，一个培训核心和一个社区参与核心。