A NEUROETHOLOGICAL APPROACH TO MEMORY AND COGNITION IN MONKEYS

猴子记忆和认知的神经行为学方法

• 批准号: 8172374
• 负责人: ROBERT L. HAMPTON
• 金额: $ 4.39万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172374
• 关键词: Animals; Behavioral Paradigm; Clip; Cognition; Complex; Computer Retrieval of Information on Scientific Projects Database; Development; Discrimination; Film; Funding; Grant; Human; Individual; Institution; Laboratories; Learning; Libraries; Memory; Monkeys; Performance; Primates; Process; Relative (related person); Research; Research Personnel; Resources; Running; Social Behavior; Social Controls; Social Dominance; Social Interaction; Source; Stimulus; Structure; Testing; Training; United States National Institutes of Health; face perception; insight; neurobehavioral; pressure; response; social; social cognition

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is frequently hypothesized that primate cognition has evolved in response to selective pressures for the ability to process complex social information (e.g., Tomasello & Call, 1997). The social complexity hypothesis suggests that central insights into the structure and function of primate cognition will be achieved through the study of social cognition; however, few neurobehavioral studies of primate cognition have made use of social stimuli. There is a critical need for studies of social cognition in primates. Historically, one of the issues retarding the development of such studies in monkeys is the difficulty in presenting animals with experimentally-controlled social stimuli. Our objective in this project is to develop a new behavioral paradigm for studying primate social cognition that permits reliable experimental control of social stimuli by using digitally-edited video clips of monkeys interacting. We have collected a library of primate social behavior videos at the field station using monkeys in Dr. Mark Wilson's laboratory. We have filmed 14 individual monkeys engaged in a variety of social behaviors and have edited many of these clips together to make realistic artificial social interactions. A group of 6 monkeys have been successfully trained to make dominance discriminations using these video clips. A variety of probe tests have revealed that the monkeys' performance is not controlled entirely by dominance information, however, and further probes are currently being run in an effort to determine what other information the monkeys may attend to in these videos. Other probes have demonstrated that the monkeys do remember individuals seen in the videos, and their relative rank. We have discovered close parallels with human face perception in monkeys. We have successfully trained monkeys on a transitive inference task thought to be similar to dominance hierarchy learning.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 人们经常假设灵长类的认知是在对处理复杂社会信息的能力的选择压力下进化的(例如，Tomasello&Call，1997)。社会复杂性假说认为，对灵长类认知的结构和功能的中心洞察将通过对社会认知的研究来实现；然而，很少有关于灵长类认知的神经行为研究利用社会刺激。 迫切需要对灵长类动物的社会认知进行研究。从历史上看，阻碍猴子这类研究发展的一个问题是，向动物呈现实验控制的社会刺激存在困难。我们在这个项目中的目标是开发一种新的行为范式来研究灵长类动物的社会认知，通过使用经过数字编辑的猴子互动的视频剪辑来实现对社会刺激的可靠实验控制。 我们在野外站收集了一个灵长类动物的社会行为视频资料库，这些视频是在马克·威尔逊博士的实验室里用猴子拍摄的。我们已经拍摄了14只参与各种社交行为的猴子个体，并将其中的许多片段剪辑在一起，以制作逼真的人工社交互动。一组6只猴子已经被成功地训练成使用这些视频片段进行优势辨别。 然而，各种探测测试显示，猴子的表现并不完全受优势信息的控制，目前正在进行进一步的探测，以确定猴子在这些视频中可能关注的其他信息。其他探测表明，猴子确实记得视频中看到的个体，以及它们的相对排名。 我们在猴子身上发现了与人类面部感知的密切相似之处。我们已经成功地训练猴子完成一项传递性推理任务，该任务被认为类似于优势等级学习。