A NEUROETHOLOGICAL APPROACH TO MEMORY AND COGNITION IN MONKEYS

猴子记忆和认知的神经行为学方法

• 批准号: 8357432
• 负责人: ROBERT L. HAMPTON
• 金额: $ 3.29万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357432
• 关键词: Accounting; Animals; Behavioral Paradigm; Clip; Cognition; Complex; Development; Discrimination; Film; Funding; Grant; Human; Individual; Learning; Libraries; Link; Memory; Monkeys; National Center for Research Resources; Performance; Primates; Principal Investigator; Process; Research; Research Infrastructure; Resources; Social Behavior; Social Controls; Social Dominance; Social Interaction; Source; Stimulus; Structure; Techniques; Testing; Training; United States National Institutes of Health; cost; face perception; insight; neurobehavioral; pressure; response; social; social cognition; social group

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Primate cognition may have evolved in response to selective pressures for the ability to process complex social information. This suggests that central insights into the structure and function of primate cognition will be achieved through the study of social cognition. However, few neurobehavioral studies of primate cognition have made use of social stimuli. There is a critical need for studies of social cognition in primates. One of the issues retarding the development of such studies in monkeys is the difficulty in presenting animals with experimentally-controlled social stimuli. Our objective in this project is to develop behavioral paradigms for studying primate social cognition that permit reliable experimental control of social stimuli using digitally-edited video clips. We have created a library of primate social behavior videos. We filmed individual monkeys engaged in a variety of social behaviors and have edited these clips together to make realistic artificial social interactions. Monkeys have been trained to make dominance discriminations using these video clips. Other tests have shown that the monkeys remember individuals seen in the videos. We have discovered close parallels with human face perception in monkeys. We have successfully trained monkeys on a transitive inference task thought to be similar to dominance hierarchy learning. We have shown that monkeys readily "link" ordered lists, indicating that associative strength cannot account for performance in transitive inference tasks. We have developed techniques for automatically testing monkey cognition in large social groups.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 灵长类动物的认知能力可能是为了应对处理复杂社会信息的选择压力而进化的。这表明，对灵长类认知的结构和功能的核心见解将通过对社会认知的研究来实现。然而，很少有灵长类动物认知的神经行为研究利用社会刺激。对灵长类动物社会认知的研究是迫切需要的。阻碍在猴子身上进行这种研究的问题之一是，很难向动物提供实验控制的社会刺激。我们在这个项目中的目标是开发研究灵长类动物社会认知的行为范式，允许使用数字编辑的视频剪辑对社会刺激进行可靠的实验控制。 我们建立了一个灵长类动物社会行为视频库。我们拍摄了参与各种社会行为的单个猴子，并将这些片段编辑在一起，以制作逼真的人工社会互动。猴子已经被训练使用这些视频剪辑进行优势歧视。其他测试表明，猴子记得视频中看到的人。我们在猴子身上发现了与人类面部感知的密切相似之处。我们已经成功地训练了猴子的传递性推理任务，这被认为是类似于优势层次学习。我们已经表明，猴子很容易“链接”有序列表，这表明关联强度不能解释传递性推理任务的性能。我们已经开发出在大型社会群体中自动测试猴子认知能力的技术。