Career Development in Pediatric and Medical Oncology

儿科和肿瘤内科的职业发展

• 批准号: 8130736
• 负责人: IRWIN D BERNSTEIN
• 金额: $ 37.74万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8130736
• 关键词: Area; Biology; Biomedical Research; Biometry; Bone Marrow Transplantation; Childhood; Clinical; Clinical Investigator; Clinical Oncology; Clinical Protocols; Clinical Research; Clinical Skills; Clinical Trials Design; Data; Evaluation; Fellowship; Fred Hutchinson Cancer Research Center; Funding; Goals; Hematology; Hematopoiesis; Human; Immunogenetics; Immunotherapy; Laboratories; Laboratory Research; Malignant - descriptor; Medical Oncology; Medical center; Medicine; Patients; Pediatric Hospitals; Pediatric Oncology; Physicians; Qualifying; Research; Research Project Grants; Research Training; Services; Training; Training Programs; Translating; Transplantation; Transplantation Immunology; Universities; Washington; cancer care; career; career development; experience; gene therapy; neuro-oncology; oncology; pediatric department; programs; protocol development; research facility; tool

DESCRIPTION (provided by applicant): We are requesting funds for a research career development program in Pediatric and Medical Oncology at the Fred Hutchinson Cancer Research Center and the University of Washington. The Career Development Program will interface with our Pediatric and Medical Oncology Research Training Programs at the Fred Hutchinson Cancer Research Center (FHCRC) and the Departments of Pediatrics and Medicine at the University of Washington (UW) with the goal of developing clinical investigators. It will support physicians who have completed three years of fellowship training in the pediatric or medical oncology training programs. Prior to entry into the program, fellows will have acquired clinical skills and basic laboratory tools of modern biology. Those most qualified and motivated to enter into investigative endeavors in clinical research will be selected. During their two to three years supported by the career development program, trainees will gain the tools and experience necessary to conduct clinical research, translate their findings to patients, and generate sufficient data to help establish independent research careers. The aim of their projects will be to contribute new and useful information relevant to clinical oncology and to develop the clinical research capabilities of the trainees. Clinical research projects in the areas of bone marrow transplantation, immunology and immunotherapy, transplantation biology, normal and malignant hematopoiesis, human immunogenetics, neurooncology, molecular biology, and gene therapy, as well as other programs, will be used for training. Trainees will also gain experience in clinical protocol development, conduct, and evaluation, and will receive didactic training, in biostatistics, clinical trial design and biomedical research integrity. This program involves the laboratory and clinical research facilities of the Fred Hutchinson Cancer Research Center and the University of Washington, and the clinical facilities of the Seattle Cancer Care Alliance and the Division of Hematology-Oncology at the Children's Hospital and Regional Medical Center, the primary clinical pediatric service of the University of Washington.

描述（由申请人提供）：我们正在申请弗雷德哈钦森癌症研究中心和华盛顿大学儿科和内科肿瘤学研究职业发展计划的资金。职业发展计划将与我们在弗雷德哈钦森癌症研究中心（FHCRC）和华盛顿大学（UW）儿科和医学系的儿科和内科肿瘤学研究培训计划对接，目标是培养临床研究者。它将支持那些在儿科或医学肿瘤学培训计划中完成了三年奖学金培训的医生。在进入该计划之前，研究员将获得现代生物学的临床技能和基本实验室工具。将选出那些最有资格和积极性参与临床研究调查工作的人。 在职业发展计划支持的两到三年内，学员将获得进行临床研究所需的工具和经验，将他们的发现转化为患者，并生成足够的数据以帮助建立独立的研究职业。他们的项目的目的是提供与临床肿瘤学相关的新的有用信息，并培养学员的临床研究能力。骨髓移植、免疫学和免疫治疗、移植生物学、正常和恶性造血、人类免疫遗传学、神经肿瘤学、分子生物学和基因治疗等领域的临床研究项目将用于培训。学员还将获得临床方案制定，实施和评估方面的经验，并将接受生物统计学，临床试验设计和生物医学研究完整性方面的教学培训。 该计划涉及Fred哈钦森癌症研究中心和华盛顿大学的实验室和临床研究机构，以及西雅图癌症护理联盟和儿童医院和区域医疗中心血液肿瘤科的临床机构，华盛顿大学的主要临床儿科服务。