CTSA INFRASTRUCTURE FOR AIDS RESEARCH

本分项目是CTSA供资的估计百分比，即 被用于广泛的研究领域(艾滋病研究、儿科研究或 临床试验)。列出的总成本仅是对CTSA金额的估计 用于这一研究领域的基础设施，而不是由 授予子项目或子项目工作人员的NCRR补助金。 我们建议发展翻译健康科学研究所(ITHS)，以支持翻译研究在我们的环境中日益跨学科和协作的性质。该研究所将大大加强我们地区三个主要研究机构--华盛顿大学(UW)、弗雷德·哈钦森癌症研究中心(FHCRC)以及儿童医院和地区医学中心(CHRMC)之间正在进行的合作。此外，ITH将加强与团体健康合作社、贝纳罗亚研究所以及通过威斯康星州大学开发的现有临床和研究基础设施的翻译研究联系，这些基础设施横跨WWAMI五个州。最后，ITHS将作为一个全面的翻译研究合作伙伴，与社区开展科学合作，为交流和基于研究的互动创造坚实的途径。通过国际翻译研究所，我们将把我们地区丰富的翻译研究资源汇聚在一个共同的基础设施中，与机构基础设施协同工作。该研究所将作为一个“协作室”发挥作用；一个横跨所有机构的结构，以促进合作、职业发展、教育和翻译研究过程本身。ITHS的结构将实现以下总体目标：(1)加强和进一步发展我们环境内和社区内的合作网络，(2)提供所需的教育计划和职业发展，以加强各级翻译研究，(3)支持创新研究、研究基础设施和将创新技术整合到翻译研究中，以及(4)培养一个将翻译研究作为我们环境中的优先事项的社区。该研究所将调整资源，以满足成员不断发展的研究需求。为了实现这种灵活性，我们将使用一种动态的评价战略，强调以系统为基础的方法，评价过程是连续的，经常评估资源和活动，然后调整短期目标，以便更快地对长期结果产生影响。其结果是不断改进流程，最大限度地提高ITHS在伙伴机构和社区内和跨伙伴机构和社区支持和促进创新翻译研究的能力。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. We propose to develop the Institute of Translational Health Sciences (ITHS) to support the increasingly nterdisciplinary and collaborative nature of translational research in our environment. The ITHS will significantly enhance the ongoing collaboration between three major research institutions in our region-the University of Washington (UW), Fred Hutchinson Cancer Research Center (FHCRC), and Children's Hospital and Regional Medical Center (CHRMC). Furthermore, the ITHS will strengthen translational research ties with Group Health Cooperative, the Benaroya Research Institute, and existing clinical and research infrastructure developed through the UW across the 5 state WWAMI region. Finally, the ITHS will gnite scientific collaboration with the community as a full translational research partner creating solid pathways of communication and research based interactions. Through the ITHS, we will bring together the rich pool of translational research resources in our region within a common infrastructure that synergizes with institutional infrastructures. The ITHS will function as a "collaboratory"; a structure that spans all institutions to foster collaboration, career development, education, and the translational research process itself. The ITHS will be structured to achieve the following overarching goals: (1) Enhance and further develop collaboration networks within.our environment and into the community, (2) Provide the educational programs and career development needed to strengthen translational research at all levels, (3) Support innovative research, research infrastructure and the integration of innovative technologies into translational research, and, (4) Foster a community that values translational research as a priority in our environment. The ITHS will adapt resources to meet the members evolving research needs. To achieve such flexibility we will use an evaluation strategy that is dynamic and emphasizes a systems based approach, where the evaluation'process is continuous with frequent assessment of resources and activity followed by an adjustment of short term goals so that more rapid impact can be made in long term outcomes. The result is a continuous process improvement that wil maximize the ITHS' ability to support and facilitate innovative translational research within and across partner institutions and the community.