CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 我们建议发展转化健康科学研究所（INTS），以支持我们环境中越来越多的跨学科和协作性质的转化研究。该项目将大大加强我们地区三个主要研究机构--华盛顿大学（UW）、弗雷德哈钦森癌症研究中心（FHCRC）和儿童医院和地区医疗中心（CHRMC）--之间的持续合作。此外，该研究所将加强与集团健康合作社，贝纳罗亚研究所，以及现有的临床和研究基础设施，通过整个5个州WWAMI地区的华盛顿大学开发的转化研究关系。最后，作为一个全面的转化研究合作伙伴，该研究所将与社区开展科学合作，为基于交流和研究的互动创造坚实的途径。通过该项目，我们将把本地区丰富的转化研究资源汇集在一个与机构基础设施协同作用的共同基础设施中。该研究所将作为一个“合作实验室”;一个跨越所有机构的结构，以促进合作，职业发展，教育和转化研究过程本身。该战略的结构将实现以下总体目标：（1）加强和进一步发展合作网络内。我们的环境和进入社区，（2）提供教育计划和职业发展需要加强各级转化研究，（3）支持创新研究，研究基础设施和创新技术融入转化研究，和，（4）培养一个重视翻译研究的社区，将其作为我们环境中的优先事项。该研究所将调整资源，以满足成员不断变化的研究需求。为了实现这种灵活性，我们将采用一种动态的评价战略，强调以系统为基础的方法，在这种方法中，评价过程是连续的，经常评估资源和活动，然后调整短期目标，以便在长期成果中产生更快的影响。其结果是一个持续的过程改进，将最大限度地提高CNAS的能力，以支持和促进创新的翻译研究内部和跨合作机构和社区。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. We propose to develop the Institute of Translational Health Sciences (ITHS) to support the increasingly nterdisciplinary and collaborative nature of translational research in our environment. The ITHS will significantly enhance the ongoing collaboration between three major research institutions in our region-the University of Washington (UW), Fred Hutchinson Cancer Research Center (FHCRC), and Children's Hospital and Regional Medical Center (CHRMC). Furthermore, the ITHS will strengthen translational research ties with Group Health Cooperative, the Benaroya Research Institute, and existing clinical and research infrastructure developed through the UW across the 5 state WWAMI region. Finally, the ITHS will gnite scientific collaboration with the community as a full translational research partner creating solid pathways of communication and research based interactions. Through the ITHS, we will bring together the rich pool of translational research resources in our region within a common infrastructure that synergizes with institutional infrastructures. The ITHS will function as a "collaboratory"; a structure that spans all institutions to foster collaboration, career development, education, and the translational research process itself. The ITHS will be structured to achieve the following overarching goals: (1) Enhance and further develop collaboration networks within.our environment and into the community, (2) Provide the educational programs and career development needed to strengthen translational research at all levels, (3) Support innovative research, research infrastructure and the integration of innovative technologies into translational research, and, (4) Foster a community that values translational research as a priority in our environment. The ITHS will adapt resources to meet the members evolving research needs. To achieve such flexibility we will use an evaluation strategy that is dynamic and emphasizes a systems based approach, where the evaluation'process is continuous with frequent assessment of resources and activity followed by an adjustment of short term goals so that more rapid impact can be made in long term outcomes. The result is a continuous process improvement that wil maximize the ITHS' ability to support and facilitate innovative translational research within and across partner institutions and the community.