CTSA INFRASTRUCTURE FOR PEDIATRIC CLINICAL TRIALS

用于儿科临床试验的 CTSA 基础设施

• 批准号: 8365201
• 负责人: Mary L. Disis
• 金额: $ 48万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-06-26
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365201
• 关键词: Childhood; Clinical Trials; Institutes; Research Infrastructure; translational health science

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. We propose to develop the Institute of Translational Health Sciences (ITHS) to support the increasingly nterdisciplinary and collaborative nature of translational research in our environment. The ITHS will significantly enhance the ongoing collaboration between three major research institutions in our region-the University of Washington (UW), Fred Hutchinson Cancer Research Center (FHCRC), and Children's Hospital and Regional Medical Center (CHRMC). Furthermore, the ITHS will strengthen translational research ties with Group Health Cooperative, the Benaroya Research Institute, and existing clinical and research infrastructure developed through the UW across the 5 state WWAMI region. Finally, the ITHS will gnite scientific collaboration with the community as a full translational research partner creating solid pathways of communication and research based interactions. Through the ITHS, we will bring together the rich pool of translational research resources in our region within a common infrastructure that synergizes with institutional infrastructures. The ITHS will function as a "collaboratory"; a structure that spans all institutions to foster collaboration, career development, education, and the translational research process itself. The ITHS will be structured to achieve the following overarching goals: (1) Enhance and further develop collaboration networks within.our environment and into the community, (2) Provide the educational programs and career development needed to strengthen translational research at all levels, (3) Support innovative research, research infrastructure and the integration of innovative technologies into translational research, and, (4) Foster a community that values translational research as a priority in our environment. The ITHS will adapt resources to meet the members evolving research needs. To achieve such flexibility we will use an evaluation strategy that is dynamic and emphasizes a systems based approach, where the evaluation'process is continuous with frequent assessment of resources and activity followed by an adjustment of short term goals so that more rapid impact can be made in long term outcomes. The result is a continuous process improvement that wil maximize the ITHS' ability to support and facilitate innovative translational research within and across partner institutions and the community.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 我们建议开发转化健康科学研究所（ITHS），以支持我们环境中转化研究越来越多的学科和协作性质。 ITHS将大大提高我们地区华盛顿大学（UW），Fred Hutchinson癌症研究中心（FHCRC），儿童医院和地区医疗中心（CHRMC）之间的三个主要研究机构之间的持续合作。此外，ITHS将加强与团体健康合作社，Benaroya研究所以及现有的临床和研究基础设施通过UW在5个州WWAMI地区开发的现有临床和研究基础设施的联系。最后，ITH将与社区进行科学合作，作为一个完整的转化研究伙伴，创造了良好的沟通和基于研究的互动的途径。通过ITHS，我们将在与机构基础设施协同作用的共同基础设施中，将丰富的转化研究资源池汇集在一起​​。 ITH将充当“协作”；跨越所有机构以促进合作，职业发展，教育和翻译研究过程本身的结构。 The ITHS will be structured to achieve the following overarching goals: (1) Enhance and further develop collaboration networks within.our environment and into the community, (2) Provide the educational programs and career development needed to strengthen translational research at all levels, (3) Support innovative research, research infrastructure and the integration of innovative technologies into translational research, and, (4) Foster a community that values translational research as a priority in our environment. ITH将调整资源以满足成员不断发展的研究需求。为了实现这种灵活性，我们将使用一种动态的评估策略，并强调一种基于系统的方法，在这种方法中，评估过程是连续的，并且经常评估资源和活动，然后调整短期目标，以便在长期成果中可以产生更快的影响。结果是一个持续的过程改进，将最大限度地提高ITH支持和促进合作伙伴机构和社区内部和促进创新的转化研究的能力。