CTSA INFRASTRUCTURE FOR CLINICAL TRIALS

CTSA 临床试验基础设施

• 批准号: 8365200
• 负责人: Mary L. Disis
• 金额: $ 287.98万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-06-26
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365200
• 关键词: Clinical Trials; Institutes; Research Infrastructure; translational health science

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. We propose to develop the Institute of Translational Health Sciences (ITHS) to support the increasingly nterdisciplinary and collaborative nature of translational research in our environment. The ITHS will significantly enhance the ongoing collaboration between three major research institutions in our region-the University of Washington (UW), Fred Hutchinson Cancer Research Center (FHCRC), and Children's Hospital and Regional Medical Center (CHRMC). Furthermore, the ITHS will strengthen translational research ties with Group Health Cooperative, the Benaroya Research Institute, and existing clinical and research infrastructure developed through the UW across the 5 state WWAMI region. Finally, the ITHS will gnite scientific collaboration with the community as a full translational research partner creating solid pathways of communication and research based interactions. Through the ITHS, we will bring together the rich pool of translational research resources in our region within a common infrastructure that synergizes with institutional infrastructures. The ITHS will function as a "collaboratory"; a structure that spans all institutions to foster collaboration, career development, education, and the translational research process itself. The ITHS will be structured to achieve the following overarching goals: (1) Enhance and further develop collaboration networks within.our environment and into the community, (2) Provide the educational programs and career development needed to strengthen translational research at all levels, (3) Support innovative research, research infrastructure and the integration of innovative technologies into translational research, and, (4) Foster a community that values translational research as a priority in our environment. The ITHS will adapt resources to meet the members evolving research needs. To achieve such flexibility we will use an evaluation strategy that is dynamic and emphasizes a systems based approach, where the evaluation'process is continuous with frequent assessment of resources and activity followed by an adjustment of short term goals so that more rapid impact can be made in long term outcomes. The result is a continuous process improvement that wil maximize the ITHS' ability to support and facilitate innovative translational research within and across partner institutions and the community.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 我们建议建立转化健康科学研究所（ITHS），以支持我们环境中日益增强的跨学科和协作性质的转化研究。 ITHS 将显着加强我们地区三个主要研究机构——华盛顿大学 (UW)、弗雷德·哈钦森癌症研究中心 (FHCRC) 以及儿童医院和地区医疗中心 (CHRMC) 之间正在进行的合作。此外，ITHS 将加强与 Group Health Cooperative、贝纳罗亚研究所以及通过威斯康星大学在 WWAMI 地区 5 个州开发的现有临床和研究基础设施的转化研究联系。最后，ITHS 将作为全面转化研究合作伙伴与社区开展科学合作，创建坚实的沟通和基于研究的互动途径。通过 ITHS，我们将把本地区丰富的转化研究资源汇集到一个与机构基础设施协同的共同基础设施中。 ITHS 将发挥“合作机构”的作用；一个跨越所有机构的结构，以促进合作、职业发展、教育和转化研究过程本身。 ITHS 的构建将实现以下总体目标：(1) 加强并进一步发展我们的环境内和社区内的协作网络，(2) 提供加强各级转化研究所需的教育计划和职业发展，(3) 支持创新研究、研究基础设施以及将创新技术整合到转化研究中，(4) 培育一个将转化研究视为我们环境中优先事项的社区。 ITHS 将调整资源以满足成员不断变化的研究需求。为了实现这种灵活性，我们将使用动态的评估策略，强调基于系统的方法，其中评估过程是连续的，经常评估资源和活动，然后调整短期目标，以便对长期结果产生更快速的影响。其结果是持续的流程改进，将最大限度地提高 ITHS 支持和促进合作机构和社区内部和跨合作机构和社区的创新转化研究的能力。